Pregnant and lactating women should be included in clinical trials for cardiovascular disease

被引：11

作者：

Assadpour, Elnaz ^{[1
]}

Van Spall, Harriette G. C. ^{[2
,3
,4
,5
]}

机构：

[1] Western Univ, Schulich Sch Med & Dent, London, ON, Canada

[2] McMaster Univ, Dept Med, Hamilton, ON, Canada

[3] McMaster Univ, Dept Hlth Res Methods Evidence & Impact, Hamilton, ON, Canada

[4] Populat Hlth Res Inst, Hamilton, ON, Canada

[5] St Josephs Healthcare Hamilton, Res Inst St Josephs, Hamilton, ON, Canada

来源：

NATURE MEDICINE | 2023年 / 29卷 / 08期

关键词：

D O I：

10.1038/s41591-023-02416-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Women who are pregnant, lactating or of childbearing potential are commonly excluded from cardiovascular randomized controlled trials - this needs to change.

引用

页码：1897 / 1899

页数：3

共 12 条

[1]

Collier Ai-Ris Y, 2019, Neoreviews, V20, pe561, DOI 10.1542/neo.20-10-e561

[2]

Filbey L., 2022, AM HEART J PLUS, V13, P100091, DOI [10.1016/j.ahjo.2022.10009, DOI 10.1016/J.AHJO.2022.10009]

[3] Improving representativeness in trials: a call to action from the Global Cardiovascular Clinical Trialists Forum [J].

Filbey, Lynaea ;

Zhu, Jie Wei ;

D'Angelo, Francesca ;

Thabane, Lehana ;

Khan, Muhammad Shahzeb ;

Lewis, Eldrin ;

Patel, Manesh R. ;

Powell-Wiley, Tiffany ;

Miranda, J. Jaime ;

Zuhlke, Liesl ;

Butler, Javed ;

Zannad, Faiez ;

Van Spall, Harriette G. C. .

EUROPEAN HEART JOURNAL, 2023, 44 (11) :921-930

[4] Participation of Women and Older Participants in Randomized Clinical Trials of Lipid-Lowering Therapies A Systematic Review [J].

Khan, Safi U. ;

Khan, Muhammad Zia ;

Subramanian, Charumathi Raghu ;

Riaz, Haris ;

Khan, Muhammad U. ;

Lone, Ahmad Naeem ;

Khan, Muhammad Shahzeb ;

Benson, Eve-Marie ;

Alkhouli, Mohamad ;

Blaha, Michael J. ;

Blumenthal, Roger S. ;

Gulati, Martha ;

Michos, Erin D. .

JAMA NETWORK OPEN, 2020, 3 (05)

[5] Increasing representation and diversity in cardiovascular clinical trial populations [J].

Michos, Erin D. ;

Van Spall, Harriette G. C. .

NATURE REVIEWS CARDIOLOGY, 2021, 18 (08) :537-538

[6] The Canadian Women's Heart Health Alliance Atlas on the Epidemiology, Diagnosis, and Management of Cardiovascular Disease in Women d Chapter 5: Sex- and Gender-Unique Manifestations of Cardiovascular Disease [J].

Pacheco, Christine ;

Mullen, Kerri-Anne ;

Coutinho, Thais ;

Jaffer, Shahin ;

Parry, Monica ;

Van Spall, Harriette G. C. ;

Clavel, Marie-Annick ;

Edwards, Jodi D. ;

Sedlak, Tara ;

Norris, Colleen M. ;

Dhukai, Abida ;

Grewal, Jasmine ;

Mulvagh, Sharon L. .

CJC OPEN, 2022, 4 (03) :243-262

[7] Use of medication for cardiovascular disease during pregnancy [J].

Pieper, Petronella G. .

NATURE REVIEWS CARDIOLOGY, 2015, 12 (12) :718-729

[8] 2018 ESC Guidelines for the management of cardiovascular diseases during pregnancy [J].

Regitz-Zagrosek, Vera ;

Roos-Hesselink, Jolien W. ;

Bauersachs, Johann ;

Blomstrom-Lundqvist, Carina ;

Cifkova, Renata ;

De Bonis, Michele ;

Iung, Bernard ;

Johnson, Mark Richard ;

Kintscher, Ulrich ;

Kranke, Peter ;

Lang, Irene Marthe ;

Morals, Joao ;

Pieper, Petronella G. ;

Presbitero, Patrizia ;

Price, Susanna ;

Rosano, Giuseppe M. C. ;

Seeland, Ute ;

Simoncini, Tommaso ;

Swan, Lorna ;

Warnes, Carole A. .

EUROPEAN HEART JOURNAL, 2018, 39 (34) :3165-+

[9] Eligibility criteria of randomized controlled trials published in high-impact general medical journals - A systematic sampling review [J].

Van Spall, Harriette G. C. ;

Toren, Andrew ;

Kiss, Alex ;

Fowler, Robert A. .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2007, 297 (11) :1233-1240

[10] Exclusion of pregnant and lactating women from COVID-19 vaccine trials: a missed opportunity [J].

Van Spall, Harriette Gillian Christine .

EUROPEAN HEART JOURNAL, 2021, 42 (28) :2724-2726

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