Flavonoids, biphenyls and xanthones from the genus Clusia: chemistry, biological activities and chemophenetics relevance

被引：2
作者：
dos Santos, Ismirna I. P. [1 ,2 ]
Silva, Maria do Carmo C. [1 ]
Ferraz, Caline G. [1 ,2 ]
Ribeiro, Paulo R. [1 ,2 ]
机构：
[1] Univ Fed Bahia, Inst Quim, Dept Quim Organ, Metabol Res Grp, Salvador, Brazil
[2] Univ Estado Bahia, Dept Ciencias Exatas & Terra, Programa Posgrad Quim Aplicada, Campus 1, Salvador, Brazil
来源：
NATURAL PRODUCT RESEARCH | 2025年 / 39卷 / 03期
关键词：
Acetate and shikimate pathways; Clusiaceae; glycosylation; polyphenols; prenylation; POLYISOPRENYLATED BENZOPHENONES; ANTIMICROBIAL ACTIVITY; CHEMICAL-CONSTITUENTS; ANTIOXIDANT ACTIVITY; KAEMPFEROL; EXTRACTS; (-)-EPICATECHIN; BIFLAVONOIDS; TOCOTRIENOL; METABOLITES;
D O I：
10.1080/14786419.2024.2330515
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Clusia is one of the most important genera of the Clusiaceae family, comprising up to 400 species. This review describes the identification of twenty-two flavonoids from Clusia species, which includes five flavonols (1-4 and 11), six flavones (5-10), one catechin (12), one flavanone (13), and nine biflavonoids (14-22). O- and C-glycosylation are frequently observed amongst these flavonoids. Furthermore, seven biphenyls (23-29) and nine xanthones (30-38) have been isolated from Clusia species. Biphenyls and xanthones show limited occurrence within the genus, but together with biosynthetic insights, they might offer important chemophenetics leads for the consolidation of the genus Clusia within the Clusiaceae family. Altogether, this work provides an overview of the chemistry of the genus Clusia in terms of flavonoids, biphenyls and xanthones, as well as it discusses biological activities and chemophenetics of the isolated compounds, when appropriate.
引用
收藏
页码：579 / 592
页数：14
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