PVF composite conductive nanofibers-based organic electrochemical transistors for lactate detection in human sweat

被引:16
作者
Shen, Yutong [1 ,2 ,3 ]
Chai, Shanshan [1 ,2 ,3 ]
Zhang, Qingling [1 ,2 ,3 ]
Zhang, Mengdi [1 ,2 ,3 ]
Mao, Xue [1 ,2 ,3 ]
Wei, Liang [1 ,2 ,3 ]
Zhou, Fenglei [4 ,5 ]
Sun, Runjun [1 ,2 ,3 ]
Liu, Chengkun [1 ,2 ,3 ]
机构
[1] Xian Polytech Univ, Sch Text Sci & Engn, Xian 710048, Peoples R China
[2] Xian Polytech Univ, Key Lab Funct Text Mat & Prod, Minist Educ, Xian 710048, Peoples R China
[3] Xian Polytech Univ, Engn Res Ctr Funct Micro Nano Text Mat, Shaanxi Coll, Xian 710048, Peoples R China
[4] UCL, Ctr Med Image Comp, Dept Med Phys & Biomed Engn, London WC1E 6BT, England
[5] Qingdao Univ, Coll Text & Clothing, Qingdao 266071, Peoples R China
关键词
Electrospinning; Oriented nanofiber bundles; Fiber-based organic electrochemical transistors; Lactate detection; Flexible wearable biosensors; CHEMICAL OXYGEN-DEMAND; PHOTOELECTROCHEMICAL SENSOR;
D O I
10.1016/j.cej.2023.146008
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The detection of lactate and other bioactive molecules is of great significance in biological research, medical testing, and environmental monitoring. Organic electrochemical transistors are a kind of biosensor devices, which can convert biological signals into electrical signals. In recent years, fiber-based organic electrochemical transistors (FECTs) provide a new approach for the construction of flexible wearable biosensors, promoting greatly the development of flexible wearable electronic products. In this study, a multilayer composite electrode was first prepared by incorporating MXene and PEDOT:PSS onto electrospun oriented polyvinyl formal (PVF) nanofiber bundle, and then assembled into FECT with high sensitivity and selectivity. Meanwhile, a wearable real-time monitoring platform was built to detect the lactate concentrations in human sweat. The results showed that MXene could act as a bridge between PEDOT:PSS and PVF, and the sensing performance of PVF/MXene/ PEDOT:PSS-based FECT was enhanced obviously. It had a wide linear response range of 1 nM-100 mM, a sensitivity of 0.442 NCR/decade, a quick response time of 0.5 s, a low detection concentration, an excellent reproducibility, and a superior anti-interference characteristic. Therefore, this work provided more possibilities for the development of wearable biosensor.
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页数:10
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