The role of circular RNA in tumor microenvironment and immunotherapy

被引:4
|
作者
He, Yu [1 ]
Huang, Qiu [1 ]
Ge, Yue [1 ]
Liu, Xiao [1 ]
Tong, Yonghua [1 ]
Shang, Haojie [1 ]
Xia, Ding [1 ]
Peng, Ejun [1 ]
Wu, Jian [1 ]
Chen, Zhiqiang [1 ]
Tang, Kun [1 ]
机构
[1] Huazhong Univ Sci & Technol, Tongji Hosp, Tongji Med Coll, Dept Urol, Wuhan, Peoples R China
基金
海南省自然科学基金; 中国国家自然科学基金;
关键词
circRNAs; Tumor microenvironment; Immunotherapy; cancer; CANCER-IMMUNOTHERAPY; LUNG-CANCER; VACCINES; EXPRESSION; RESISTANCE; CIRCRNA; HETEROGENEITY; MECHANISMS; BIOMARKER; IMMUNITY;
D O I
10.1016/j.ijbiomac.2023.124929
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cancer immunotherapy has favorable efficacy in various types of tumors, and has become an important weapon in the treatment of tumors in recent years. Long noncoding RNAs and microRNAs have been identified to play important roles in regulating cancer immunotherapy. Circular RNAs (circRNAs) are involved in the pathological process of many diseases, especially cancer. Many functions of circRNAs have been extensively studied. How-ever, the functions of circRNAs in the tumor microenvironment and cancer immunotherapy do not appear to be fully elucidated. Therefore, we review the roles of circRNAs in tumor microenvironment and cancer immunotherapy.
引用
收藏
页数:13
相关论文
共 50 条
  • [41] Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy
    Ye, Jian
    Peng, Guangyong
    ONCOIMMUNOLOGY, 2015, 4 (03): : 1 - 3
  • [42] Emerging role of ferroptosis-related circular RNA in tumor metastasis
    Meng, Yifei
    Cao, Jingdong
    Li, Yidan
    Duan, Saili
    Zhou, Zongjiang
    Li, Jinghe
    Ousmane, Diabate
    Ou, Chunlin
    Wang, Junpu
    FRONTIERS IN PHARMACOLOGY, 2023, 14
  • [43] Potential applications of nanoparticles for tumor microenvironment remodeling to ameliorate cancer immunotherapy
    Bai, Yuzhuo
    Wang, Yun
    Zhang, Xudong
    Fu, Jianhua
    Xing, Xiuli
    Wang, Chunlan
    Gao, Longlan
    Liu, Yu
    Shi, Li
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2019, 570
  • [44] A Versatile Nanoplatform for Broad-Spectrum Immunotherapy by Reversing the Tumor Microenvironment
    Chen, Ao
    Yang, Fan
    Kuang, Jing
    Xiong, Yuan
    Mi, Bo-Bin
    Zhou, Ying
    Hu, Jing-Jing
    Song, Shu-Jun
    Wan, Tao
    Wan, Zhong-Zhong
    Huang, Hong-Yang
    Li, Xin-Run
    Song, Wen
    Qiu, Wen-Xiu
    ACS APPLIED MATERIALS & INTERFACES, 2021, 13 (38) : 45335 - 45345
  • [45] Ferroptosis crosstalk in anti-tumor immunotherapy: molecular mechanisms, tumor microenvironment, application prospects
    Lu, Yining
    Xie, Xiaoting
    Luo, Lianxiang
    APOPTOSIS, 2024, 29 (11-12) : 1914 - 1943
  • [46] The role of VISTA in the tumor microenvironment
    Rabadi, Dina
    Sajani, Alia A.
    Noelle, Randolph J.
    Lines, J. Louise
    JOURNAL OF CANCER METASTASIS AND TREATMENT, 2022, 8
  • [47] Exploring the Emerging Role of the Gut Microbiota and Tumor Microenvironment in Cancer Immunotherapy
    Qiu, Qin
    Lin, Yuqi
    Ma, Yucui
    Li, Xiaoling
    Liang, Juan
    Chen, Zhiyan
    Liu, Kaifeng
    Huang, Yuge
    Luo, Hui
    Huang, Riming
    Luo, Lianxiang
    FRONTIERS IN IMMUNOLOGY, 2021, 11
  • [48] Targeting metabolism to enhance immunotherapy within tumor microenvironment
    Liang, Xiao-hui
    Chen, Xin-yi
    Yan, Yue
    Cheng, Ao-yu
    Lin, Jia-yi
    Jiang, Yi-xin
    Chen, Hong-zhuan
    Jin, Jin-mei
    Luan, Xin
    ACTA PHARMACOLOGICA SINICA, 2024, 45 (10) : 2011 - 2022
  • [49] The Tumor Microenvironment and Immunotherapy of Oropharyngeal Squamous Cell Carcinoma
    Welters, Marij J. P.
    Santegoets, Saskia J.
    van der Burg, Sjoerd H.
    FRONTIERS IN ONCOLOGY, 2020, 10
  • [50] Immunosuppressive tumor microenvironment modulation by chemotherapies and targeted therapies to enhance immunotherapy effectiveness
    Barnestein, Robby
    Galland, Loick
    Kalfeist, Laura
    Ghiringhelli, Francois
    Ladoire, Sylvain
    Limagne, Emeric
    ONCOIMMUNOLOGY, 2022, 11 (01):