Self-assembly of protein-DNA superstructures for alkaline phosphatase detection in blood

被引：8

作者：

Chang, Yangyang ^{[1
]}

Zhang, Qian ^{[1
]}

Xue, Wei ^{[1
]}

Wu, Yanfang ^{[2
]}

Liu, Yi ^{[3
]}

Liu, Meng ^{[1
]}

机构：

[1] Dalian Univ Technol, Sch Environm Sci & Technol, Key Lab Ind Ecol & Environm Engn,Minist Educ, Dalian POCT Lab, Dalian 116024, Peoples R China

[2] Univ New South Wales, Sch Chem, Sydney, NSW 2052, Australia

[3] Dalian Med Univ, Dept Neurol, Dalian Municipal Cent Hosp, Dalian 116033, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 23期

关键词：

37;

D O I：

10.1039/d3cc00228d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We designed a paper-based analytical device by integrating horseradish peroxidase (HRP)-encapsulated 3D DNA for visual detection of alkaline phosphatase (ALP). This device allows on-paper sample pre-treatment, target recognition and signal readout, enabling simple (without additional pre-treatment of blood samples) and rapid (within 23 min) determination of ALP in clinical samples.

引用

页码：3399 / 3402

页数：4

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