COVID-19 surveillance in wastewater: An epidemiological tool for the monitoring of SARS-CoV-2

被引:32
作者
Maryam, Sajida [1 ]
Ul Haq, Ihtisham [1 ,2 ,3 ]
Yahya, Galal [4 ]
Ul Haq, Mehboob [1 ]
Algammal, Abdelazeem M. [5 ]
Saber, Sameh [6 ]
Cavalu, Simona [7 ]
机构
[1] COMSATS Univ Islamabad CUI, Dept Biosci, Commiss Sci & Technol Sustainable Dev South, Islamabad, Pakistan
[2] Silesian Tech Univ, Dept Phys Chem & Polymers Technol, Gliwice, Poland
[3] Silesian Tech Univ, Joint Doctoral Sch, Gliwice, Poland
[4] Zagazig Univ, Fac Pharm, Dept Microbiol & Immunol, Zagazig, Egypt
[5] Suez Canal Univ, Fac Vet Med, Dept Bacteriol Immunol & Mycol, Ismailia, Egypt
[6] Delta Univ Sci & Technol, Fac Pharm, Dept Pharmacol, Gamasa, Egypt
[7] Univ Oradea, Fac Med & Pharm, Oradea, Romania
关键词
wastewater surveillance; point-of-care diagnostics; COVID-19; pandemic; COVID-19 surveillance system; early warning system; ACUTE RESPIRATORY SYNDROME; HUMAN PATHOGENIC VIRUSES; HUMAN ENTERIC VIRUSES; HEPATITIS-A VIRUS; ENVIRONMENTAL SURVEILLANCE; SARS CORONAVIRUS; SEWAGE; RNA; TRANSMISSION; INFECTION;
D O I
10.3389/fcimb.2022.978643
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The coronavirus disease 2019 (COVID-19) pandemic has prompted a lot of questions globally regarding the range of information about the virus's possible routes of transmission, diagnostics, and therapeutic tools. Worldwide studies have pointed out the importance of monitoring and early surveillance techniques based on the identification of viral RNA in wastewater. These studies indicated the presence of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in human feces, which is shed via excreta including mucus, feces, saliva, and sputum. Subsequently, they get dumped into wastewater, and their presence in wastewater provides a possibility of using it as a tool to help prevent and eradicate the virus. Its monitoring is still done in many regions worldwide and serves as an early "warning signal"; however, a lot of limitations of wastewater surveillance have also been identified.
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页数:18
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