A simple, sensitive and cost-effective electrochemical sensor for the determination of N-acetylcysteine

被引:7
作者
Jahani, Peyman Mohammadzadeh [1 ]
Tajik, Somayeh [2 ]
Nejadb, Fariba Garkani [2 ]
机构
[1] Bam Univ Med Sci, Sch Med, Bam, Iran
[2] Kerman Univ Med Sci, Res Ctr Trop & Infect Dis, Kerman, Iran
关键词
Zeolitic imidazolate framework-67; Ionic liquid; carbon paste electrode; metal-organic framework; nanomaterials; CARBON-PASTE ELECTRODE; VOLTAMMETRIC DETERMINATION; ELECTROCATALYTIC OXIDATION; HUMAN-PLASMA; PHARMACEUTICALS; CYSTEINE; SURFACE;
D O I
10.5599/jese.2039
中图分类号
O646 [电化学、电解、磁化学];
学科分类号
081704 ;
摘要
In the present work, we prepared a simple and novel electrochemical sensor based on zeolitic imidazolate framework-67 (ZIF-67) and ionic liquid 1-Butyl-3-methylimidazolium hexa-fluorophosphate (BMIM.PF6) modified carbon paste electrode (CPE), which was effectively used for the determination of N-acetylcysteine. The cyclic voltammetry studies demonstrated the lowest peak potential and the enhanced peak current response for N-acetylcysteine at the surface of ZIF-67/BMIM.PF6-modified CPE compared to the other CPEs due to the significant catalytic effect of ZIF-67 and BMIM.PF6, as well as the combination of them. Under the optimized conditions, the electrochemical response of ZIF-67/BMIM.PF6/CPE sensor provided a good linear relationship with N-acetylcysteine concentration from 0.04 to 435.0 mu M. The limit of detection is estimated to be 0.01 mu M for N-acetylcysteine. In further studies and measurements, the estimation of N-acetylcysteine in tablet samples confirms the usefulness of the ZIF-67/BMIM.PF6/CPE sensor.
引用
收藏
页码:61 / 74
页数:14
相关论文
共 72 条
[1]   N-acetyl-cysteine promotes angiostatin production and vascular collapse in an orthotopic model of breast cancer [J].
Agarwal, A ;
Muñoz-Nájar, U ;
Klueh, U ;
Shih, SC ;
Claffey, KP .
AMERICAN JOURNAL OF PATHOLOGY, 2004, 164 (05) :1683-1696
[2]   Self-sacrifice MOFs for heterogeneous catalysis: Synthesis mechanisms and future perspectives [J].
Ahmad, Awais ;
Khan, Safia ;
Tariq, Sadaf ;
Luque, Rafael ;
Verpoort, Francis .
MATERIALS TODAY, 2022, 55 :137-169
[3]  
Akeremale O., 2022, J CHEM REV, V4, P1, DOI [DOI 10.22034/JCR.2022.314728.1130, 10.22034/jcr.2022.314728.1130]
[4]  
Alao I.I., 2022, Adv J Chem Sect B, V4, P39, DOI DOI 10.22034/AJCB.2022.323779.1106
[5]  
Arif A. I., 2023, J Med Pharm Chem Res., V5, P598, DOI DOI 10.22034/ECC.2023.384414.1600
[6]   THE ANTIOXIDANT ACTION OF N-ACETYLCYSTEINE - ITS REACTION WITH HYDROGEN-PEROXIDE, HYDROXYL RADICAL, SUPEROXIDE, AND HYPOCHLOROUS ACID [J].
ARUOMA, OI ;
HALLIWELL, B ;
HOEY, BM ;
BUTLER, J .
FREE RADICAL BIOLOGY AND MEDICINE, 1989, 6 (06) :593-597
[7]   A hybridized nano-porous carbon reinforced 3D graphene-based epidermal patch for precise sweat glucose and lactate analysis [J].
Asaduzzaman, Md ;
Abu Zahed, Md ;
Sharifuzzaman, Md ;
Reza, Md Selim ;
Hui, Xue ;
Sharma, Sudeep ;
Do Shin, Young ;
Park, Jae Yeong .
BIOSENSORS & BIOELECTRONICS, 2023, 219
[8]   Nanostructure-based electrochemical sensor for the voltammetric determination of benserazide, uric acid, and folic acid [J].
Baghbamidi, Sakineh Esfandiari ;
Beitollahi, Hadi ;
Mohammadi, Seyed Zia ;
Tajik, Somayeh ;
Soltani-Nejad, Somayeh ;
Soltani-Nejad, Vahhab .
CHINESE JOURNAL OF CATALYSIS, 2013, 34 (10) :1869-1875
[9]  
Baghernejad B., 2022, J APPL ORGANOMETALLI, V2, P140, DOI [10.22034/jaoc.2022.154819, DOI 10.22034/JAOC.2022.154819]
[10]   Copper Nanoparticles and Reduced Graphene Oxide as an Electrode Modifier for the Development of an Electrochemical Sensing Platform for Chloroquine Phosphate Determination [J].
Barreto, Francisco Contini ;
da Silva, Martin Kassio Leme ;
Cesarino, Ivana .
NANOMATERIALS, 2023, 13 (09)