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Adverse effects of topical photodynamic therapy in rosacea - Case report
被引:2
|作者:
Sebbe-Santos, Priscilla Froes
[1
]
Miquilini, Patricia
[1
]
Pinto, Juliana Guerra
[1
]
de Menezes, Priscila Fernanda Campos
[2
,3
]
Ferreira-Strixino, Juliana
[1
]
机构:
[1] Univ Vale Paraiba, Res & Dev Inst, Lab Photobiol Appl Hlth, BR-2911 Urbanova, Brazil
[2] Herminio Ometto Fdn, Araras, SP, Brazil
[3] IFSC Univ Sao Paulo USP, Inst Fis Sao Carlos, Ave Trabalhador Sao Carlense, BR-13560970 Sao Carlos, SP, Brazil
关键词:
Rosacea;
Adverse effects;
ALA;
Photodynamic Therapy;
D O I:
10.1016/j.pdpdt.2023.103871
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Rosacea is a chronic and inflammatory skin condition, with relapses being a common characteristic. Its treatments are based on cosmetics, drugs, and the application of procedures based on high-powered light. Photodynamic Cosmetic Therapy (PCT) combines light, a photosensitizer (PS), and molecular oxygen present in tissues, generating photochemical reactions capable of causing tissue and vascular destruction, stimulating tissue repair. We report a case with an adverse effect caused by applying PCT, using 2 % 5-aminolevulinic acid (ALA 2 %), and irradiated with amber LED light associated with infrared radiation for the control of rosacea. A patient with subtype II rosacea underwent PCT treatment of 3 sessions at 21-day intervals, being evaluated using photographic images and Wood's lamp. In the first session of the therapy, an exacerbated inflammatory process was observed. Such an adverse event is estimated to be as a result of the patient using ointment containing corticosteroids for a short period. With the use of medications, it was possible to recover the appearance of the skin thoroughly, and after 21 days, the treatment sessions were performed again. Despite the complication that affected the patient in this study, positive effects were found after the pharmacological therapeutic measures were adopted.
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