METHODS FOR COMBINATION TREATMENT OF METASTATIC UVEAL MELANOMA

被引：0

作者：

Kolomiets, K., V ^{[1
,2
]}

Ponomareva, E. S. ^{[1
]}

Posypina, Yar ^{[1
]}

Mihailov, I. I. ^{[1
]}

Mandzhiev, C. B. ^{[1
]}

Povetkina, E., V ^{[1
]}

Tuguz, R. R. ^{[1
]}

Bulgakov, S. M. ^{[1
]}

Repunova, V., I ^{[1
]}

机构：

[1] Rostov State Med Univ, Rostov Na Donu, Russia

[2] Krasnoarmeiskaya 198, Novocherkassk 346400, Russia

来源：

BULLETIN OF RUSSIAN STATE MEDICAL UNIVERSITY | 2023年 / 06期

关键词：

uveal melanoma; transarterial chemoembolization; immunotherapy; carboplatin; metastatic liver disease;

D O I：

10.24075/vrgmu.2023.051

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Uveal melanoma (UM) is a rare primary malignant tumor originating from uveal melanocytes (choroid (90%), ciliary body (6%), iris (4%)) of the eye. According to the aggregate data, the tumor incidence is 5.2 cases per 1 million population. In Russia this value varies between 6.23-8 cases per 1 million adult population across the regions. UM most often spreads to the liver (89-93%). The clinical case of using transarterial chemoembolization (carboplatin) in combination with immunotherapy (nivolumab + ipilimumab) in patients with metastatic liver disease from UM is provided. The disease control within 12 months has been achieved, which, in turn, demonstrates the possibility and efficacy of multidisciplinary approach.

引用

页码：86 / 89

页数：4

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