Treatments for rare ovarian tumors: What's new?

被引：0

作者：

Lebreton, Coriolan ^{[1
,2
]}

Quesada, Stanislas ^{[3
]}

Bini, Marta ^{[4
]}

Babin, Guillaume ^{[2
,5
]}

Rossi, Lea ^{[6
]}

Chopin, Nicolas ^{[6
]}

Croce, Sabrina ^{[7
,8
]}

Hartog, Cecile ^{[6
]}

Renaud, Tiphaine ^{[9
]}

Gaillard, Anne-Lise ^{[10
]}

Petit, Adeline ^{[11
]}

Serre, Anne-Agathe ^{[12
]}

Tredan, Olivier ^{[13
]}

Rowinski, Elise ^{[13
]}

Cockenpot, Vincent ^{[14
]}

Treilleux, Isabelle ^{[14
]}

Rousset-Jablonski, Christine ^{[6
]}

Meeus, Pierre ^{[6
]}

Guyon, Frederic

Ray-Coquard, Isabelle ^{[15
]}

机构：

[1] Inst Bergonie, Dept oncol med, Bordeaux, France

[2] Univ Bordeaux, ARTiSt Lab, Inserm U1312, Bordeaux, France

[3] Inst reg Canc Montpellier, Dept oncol med, Montpellier, France

[4] Inst Nazl Tumori, Milan, Italy

[5] Inst Bergonie, Dept Chirurg, Bordeaux, France

[6] Ctr Leon Berard, Dept Chirurg, Lyon, France

[7] Inst Bergonie, Dept biopathol, Bordeaux, France

[8] Univ Bordeaux, SARCOTARGET Lab, Inserm U1312, Bordeaux, France

[9] Inst Bergonie, Dept gynecol med, Bordeaux, France

[10] Inst Bergonie, Dept radiol, Bordeaux, France

[11] Inst Bergonie, Dept radiotherapie & curietherapie, Bordeaux, France

[12] Ctr Leon Berard, Dept radiotherapie & curietherapie, Lyon, France

[13] Ctr Leon Berard, Dept oncol med, Lyon, France

[14] Ctr Leon Berard, Dept biopathol, Lyon, France

[15] Univ Claude Bernard Lyon 1, Hlth Serv & performance Res lab EA HESPER 7425, Lyon, France

来源：

BULLETIN DU CANCER | 2023年 / 110卷 / 7-8期

关键词：

Rare gynecological; malignancies; Rare ovarian malignancies; Expert networks; Clinical trials; Personalized medicine; CLEAR-CELL CARCINOMA; PEMBROLIZUMAB MONOTHERAPY; CANCER; CHEMOTHERAPY; MULTICENTER; CONSENSUS; BEVACIZUMAB; THERAPY; TRIALS;

D O I：

10.1016/j.bulcan.2023.03.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Even if each rare ovarian tumor (ROT) has a low incidence, the sum of all these entities represents almost the half of all ovarian neoplasms. Thus, development of dedicated clinical trial emerged as a prerequisite to improve their managements. Owing to the spreading of dedicated institutional networks and (supra)national collaborations, the number of clinical trials has increased the past few years, with different types of trials; while some focused on specific molecular features, others assessed innovative molecules. Furthermore, relevant randomized clinical trials were designed as a mean to position new treatment options. Currently, innovative molecular-driven trials, based on master protocol trials are emerging and may shed light towards the improvement of personalized medicine regarding ROT.

引用

页码：818 / 824

页数：7

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