Discovery, mode of action, resistance mechanisms, and plan of action for sustainable use of Group 14 herbicides

被引：26

作者：

Barker, Abigail L. ^{[1
]}

Pawlak, John ^{[2
]}

Duke, Stephen O. ^{[3
]}

Beffa, Roland ^{[4
]}

Tranel, Patrick J. ^{[5
]}

Wuerffel, Joe ^{[6
]}

Young, Bryan ^{[7
]}

Porri, Aimone ^{[8
]}

Liebl, Rex ^{[9
]}

Aponte, Raphael ^{[9
]}

Findley, Douglas ^{[9
]}

Betz, Michael ^{[8
]}

Lerchl, Jens ^{[8
]}

Culpepper, Stanley ^{[10
]}

Bradley, Kevin ^{[11
]}

Dayan, Franck E. ^{[1
,12
]}

机构：

[1] Colorado State Univ, Agr Biol, Ft Collins, CO USA

[2] Valent USA, Walnut Creek, CA USA

[3] Univ Mississippi, Natl Ctr Nat Prod Res, University, MS USA

[4] Herbicide ResistanceAct Comm HRAC, Liederbach, Germany

[5] Univ Illinois, Dept Crop Sci, Urbana, IL USA

[6] Syngenta, Vero Beach, FL USA

[7] Purdue Univ, Dept Bot & Plant Pathol, W Lafayette, IN USA

[8] BASF SE, Limburgerhof, Germany

[9] BASF Corp, Res Triangle Pk, NC USA

[10] Univ Georgia, Dept Crop & Soil Sci, Tifton, GA USA

[11] Univ Missouri, Div Plant Sci, Columbia, MO USA

[12] Colorado State Univ, 1177 Campus Delivery, Ft Collins, CO 80523 USA

来源：

WEED SCIENCE | 2023年 / 71卷 / 03期

基金：

美国食品与农业研究所;

关键词：

Biorational herbicide design; protoporphyrinogen oxidase; resistance; resistance management; resistance screening; WATERHEMP AMARANTHUS-TUBERCULATUS; PROTOPORPHYRINOGEN-IX OXIDASE; NONTARGET SITE RESISTANCE; PPO-INHIBITING HERBICIDES; MANAGEMENT STRATEGIES; CONFERS RESISTANCE; ACIFLUORFEN-METHYL; WEED-CONTROL; COVER CROP; POPULATION;

D O I：

10.1017/wsc.2023.15

中图分类号：

S3 [农学（农艺学）];

学科分类号：

0901 ;

摘要：

Protoporphyrinogen oxidase (PPO)-inhibiting herbicides remain an important and useful chemistry 60 yr after their first introduction. In this review, based on topics introduced at the Weed Science Society of America 2021 symposium titled "A History, Overview, and Plan of Action on PPO Inhibiting Herbicides," we discuss the current state of PPO-inhibiting herbicides. Renewed interest in the PPO-inhibiting herbicides in recent years, due to increased use and increased cases of resistance, has led to refinements in knowledge regarding the mechanism of action of PPO inhibitors. Herein we discuss the importance of the two isoforms of PPO in plants, compile a current knowledge of target-site resistance mechanisms, examine non-target site resistance cases, and review crop selectivity mechanisms. Consistent and reproducible greenhouse screening and target-site mutation assays are necessary to effectively study and compare PPO-inhibitor resistance cases. To this end, we cover best practices in screening to accurately identify resistance ratios and properly interpret common screens for point mutations. The future of effective and sustainable PPO-inhibitor use relies on development of new chemistries that maintain activity on resistant biotypes and the promotion of responsible stewardship of PPO inhibitors both new and old. We present the biorational design of the new PPO inhibitor trifludimoxazin to highlight the future of PPO-inhibitor development and discuss the elements of sustainable weed control programs using PPO inhibitors, as well as how responsible stewardship can be incentivized. The sustained use of PPO inhibitors in future agriculture relies on the effective and timely communication from mode of action and resistance research to agronomists, Extension workers, and farmers.

引用

页码：173 / 188

页数：16

共 121 条

[1] Genetic variation associated with PPO-inhibiting herbicide tolerance in sorghum [J].