Effects of chronic abamectin stress on growth performance, digestive capacity, and defense systems in red swamp crayfish (Procambarus clarkii)

被引：5

作者：

Guan, Tianyu ^{[1
,2
]}

Wang, Long ^{[1
,2
]}

Hu, Meng ^{[1
]}

Zhu, Qianqian ^{[1
]}

Cai, Lin ^{[1
]}

Wang, Yurui ^{[1
]}

Xie, Peng ^{[1
]}

Feng, Jianbin ^{[2
,3
]}

Wang, Hui ^{[1
]}

Li, Jiale ^{[2
,3
]}

机构：

[1] Huaiyin Normal Univ, Jiangsu Collaborat Innovat Ctr Reg Modern Agr & En, Huaian 223300, Peoples R China

[2] Shanghai Ocean Univ, Key Lab Freshwater Aquat Genet Resources, Minist Agr, Shanghai 201306, Peoples R China

[3] Shanghai Ocean Univ, Natl Demonstrat Ctr Expt Fisheries Sci Educ, Shanghai 201306, Peoples R China

来源：

AQUATIC TOXICOLOGY | 2024年 / 268卷

关键词：

Procambarus clarkii; Abamectin; Growth performance; Digestive capacity; Antioxidation; Nonspecific immunity; CADMIUM EXPOSURE; OXIDATIVE STRESS; KNOCKDOWN; ECDYSONE; ENZYMES; CLONING; ACID;

D O I：

10.1016/j.aquatox.2024.106861

中图分类号：

Q17 [水生生物学];

学科分类号：

071004 ;

摘要：

Abamectin is a globally used pesticide, which is one of 16-member macrocyclic lactones compound. As an environmental contaminant, pesticide residues pose a great threat to the health and survival of aquatic animals. Procambarus clarkii is one of the most important economic aquatic animals in China. It is necessary to explore the toxic mechanism of abamectin to P. clarkii. In this study, the toxic mechanism of abamectin to P. clarkii was investigated by 0, 3 and 6 mu g/L abamectin stress for 28 days. The digestive-, antioxidant- and immune- related enzymes activities, genes expression levels, and histological observations were analytical indicators of growth performance, digestive capacity, and defense systems. The results in this study showed that with abamectin concentration increasing, the growth of P. clarkii was stunted significantly, and the mortality rate increased significantly. With exposure time and abamectin concentration increasing, the expression levels of related genes, the activities of digestive-, antioxidant-, and immune- related enzymes decreased ultimately. Moreover, through histological observation, it was found that with abamectin concentration increasing, the hepatopancreas, muscle, and intestine were damaged. As elucidated by the results, once abamectin exists in the environment for a long time, even low doses will threaten to healthy growth and survival of P. clarkii. This study explored the potential toxicity and the toxic mechanism of abamectin to P. clarkii, and provides a theoretical basis for further study on the toxicity of pesticides to aquatic animals.

引用

页数：9