Synthesis and antimicrobial activity of novel (1-phenyl-1H-1,2,3-triazo-4-yl) methyl-2-acetamido-1-phenyl-1H-benzo[f]chromene-3-carboxylate and 2-amino-octahydro-4-phenyl-2H-chromene-3-carbonitrile

被引：1

作者：

Shamili, Sriramoju ^{[1
]}

Siddoju, Kavitha ^{[1
]}

Chandrakala, G. ^{[2
]}

Farheen, Sd Ishrath ^{[2
]}

机构：

[1] Chaitanya, Dept Chem, Warangal Urban 506001, Telangana, India

[2] Vaagdevi Degree & PG Coll, Dept Microbiol, Warangal Urban 506001, Telangana, India

来源：

INDIAN JOURNAL OF CHEMISTRY | 2023年 / 62卷 / 05期

关键词：

3-Amino-1; H; -chromene-2-carbonitriles; Chromenes; Multicomponent reaction; Chloramphenicol; Amphotericin-B; DERIVATIVES;

D O I：

10.56042/ijc.v62i5.1423

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of novel (1-phenyl-1H-1,2,3-triazol-4-yl)methyl-2-acetamido-1-phenyl-1H-benzo[f] benzo[f]chromene-3carboxylate 6a-i compounds have been synthesised from prop-2-yn-1yl-3-acetamido-1-phenyl-1H-benzo[f]chromene-2carboxylate 5. 3-Amino-1-phenyl-1H-benzo[f]chromene-2-carbonitrile and 2-amino-4-phenyl-4a,5,6,7,8,8a-hexahydro-4Hchromene-3-carbonitrile (1 and 2a) are generated when benzaldehyde, 0-naphthol, (or) cyclohexanol, and malononitrile are incorporated into the mixture. Activity of two conventional antibiotics, Chloramphenicol and Amphotericin-B, have been compared to the antibacterial and antifungal properties of the prepared synthetic compounds. A study has been conducted on the spectroscopic properties of Schlenter products.

引用

页码：445 / 453

页数：9

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