Pilot, open-label, single-arm clinical trial evaluating the efficacy of topical crisaborole for steroid refractory morphea

被引：3
|
作者：
Petty, Amy J. [1 ]
Emge, Drew A. [1 ]
Blanchard, Sarah K. [1 ]
Selim, Maria Angelica [2 ]
Scoggins, Kim [1 ]
Liu, Beiyu [3 ]
Green, Cynthia L. [3 ]
Cardones, Adela R. [4 ,5 ]
机构：
[1] Duke Univ, Dept Dermatol, Durham, NC USA
[2] Duke Univ, Dept Pathol, Div Dermatopathol, Durham, NC USA
[3] Duke Univ, Dept Biostat & Bioinformat, Sch Med, Durham, NC USA
[4] Univ Kansas, Med Ctr, Dept Internal Med, Div Dermatol, Kansas City, KS USA
[5] Univ Kansas, Med Ctr, Dept Internal Med, Div Dermatol, 3901 Rainbow Blvd, Kansas City, KS 66160 USA
来源：
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2023年 / 89卷 / 02期
关键词：
clinical trial; crisaborole; fibrosis; morphea; PDE4; CHILDREN; SAFETY;
D O I：
10.1016/j.jaad.2023.03.052
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
[No abstract available]
引用
收藏
页码：390 / 392
页数：3
相关论文
共 50 条
  • [21] Surufatinib plus toripalimab in patients with advanced solid tumors: a single-arm, open-label, phase 1 trial
    Yanshuo Cao
    Ming Lu
    Yu Sun
    Jifang Gong
    Jie Li
    Zhihao Lu
    Jian Li
    Xiaotian Zhang
    Yan Li
    Zhi Peng
    Jun Zhou
    Xicheng Wang
    Lin Shen
    Journal of Cancer Research and Clinical Oncology, 2023, 149 : 779 - 789
  • [22] A single-arm open-label clinical trial of autologous epidermal cell transplantation for stable vitiligo: A 30-month follow-up
    Orouji, Zahra
    Bajouri, Amir
    Ghasemi, Mahshid
    Mohammadi, Parvaneh
    Fallah, Nasrin
    Shahbazi, Atefeh
    Rezvani, Mohammad
    Vaezirad, Fatemeh
    Khalajasadi, Zahra
    Alizadeh, Ahad
    Taghiabadi, Ehsan
    Dashtbozorgi, Sara
    Aghdami, Raheleh
    Hosseini, Seyedeh Esmat
    Bahahrvand, Hossein
    Shafieyan, Saeed
    Aghdami, Nasser
    JOURNAL OF DERMATOLOGICAL SCIENCE, 2018, 89 (01) : 52 - 59
  • [23] Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial
    Fakhouri, Fadi
    Hourmant, Maryvonne
    Campistol, Josep M.
    Cataland, Spero R.
    Espinosa, Mario
    Gaber, A. Osama
    Menne, Jan
    Minetti, Enrico E.
    Provot, Francois
    Rondeau, Eric
    Ruggenenti, Piero
    Weekers, Laurent E.
    Ogawa, Masayo
    Bedrosian, Camille L.
    Legendre, Christophe M.
    AMERICAN JOURNAL OF KIDNEY DISEASES, 2016, 68 (01) : 84 - 93
  • [24] Efficacy and safety evaluation of low-intensity extracorporeal shock wave therapy on prostatitis-like symptoms: An open-label, single-arm trial
    Jin, Chen
    Zhang, Song
    Mo, Fan
    Zhang, Meng
    Meng, Jialin
    Bian, Zichen
    Fu, Ziyue
    Fang, Qiaozhou
    Kong, Xiangbin
    Feng, Bin
    Wang, Zhiping
    Jiang, Zhancheng
    Chen, Ming
    Zhang, Li
    Song, Zhengyao
    Hao, Zongyao
    Liang, Chaozhao
    ANDROLOGIA, 2022, 54 (01)
  • [25] Seraprevir and sofosbuvir for treatment of chronic hepatitis C virus infection: A single-arm, open-label, phase 3 trial
    Kong, Fei
    Wen, Xiaoyu
    Wen, Xiaofeng
    Wang, Xiaozhong
    Wu, Guicheng
    Lin, Shide
    Wang, Li
    Xing, Huichun
    Yan, Xuebing
    Zheng, Sujun
    Ning, Qin
    Wang, Zheng
    Zhang, Liaoyun
    Lin, Jianmei
    Tong, Zhaowei
    Huang, Chengyu
    Su, Minghua
    Tong, Lixin
    Jia, Jidong
    Xin, Yongning
    Zhu, Qingjing
    Wang, Jing
    Chen, Li
    Li, Xiaowen
    Wu, Xuegang
    Niu, Duan
    Liu, Quan
    Wei, Wei
    Zhang, Yuexin
    Li, Guangming
    Niu, Junqi
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2021, 36 (09) : 2375 - 2382
  • [26] Hydrogen in Patients With Corticosteroid-Refractory/Dependent Chronic Graft-Versus-Host-Disease: A Single-Arm, Multicenter, Open-Label, Phase 2 Trial
    Qian, Liren
    Liu, Miao
    Shen, Jianliang
    Cen, Jian
    Zhao, Defeng
    FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [27] Loncastuximab tesirine in Chinese patients with relapsed or refractory diffuse large B-cell lymphoma: a multicenter, open-label, single-arm, phase II trial
    Lin, Ningjing
    Sun, Xiuhua
    Zhou, Hui
    Zou, Liqun
    Zhou, Keshu
    Liu, Lihong
    Yang, Haiyan
    Hu, Kai
    Cai, Qingqing
    Liu, Yao
    Jin, Jie
    Zhang, Liling
    Li, Wenyu
    Guo, Ye
    Yang, Wei
    Luo, Feng
    Wang, Zhenguang
    Zhu, Rong
    Yang, Lei
    Song, Dan
    Song, Yuqin
    Zhu, Jun
    HAEMATOLOGICA, 2025, 110 (03) : 683 - 692
  • [28] Phase 3, open-label, Russian, multicenter, single-arm trial to evaluate the immunogenicity of varicella vaccine (VARIVAX™) in healthy infants, children, and adolescents
    Paradis, Erin M.
    Tikhonov, Oleg
    Cao, Xin
    Kharit, Susanna M.
    Fokin, Aleksandr
    Platt, Heather L.
    Wittke, Frederick
    Jotterand, Veronika
    HUMAN VACCINES & IMMUNOTHERAPEUTICS, 2021, 17 (11) : 4183 - 4189
  • [29] Phase II, multi-center, open-label, single-arm clinical trial evaluating the efficacy and safety of Mycophenolate Mofetil in patients with high-grade locally advanced or metastatic osteosarcoma (ESMMO): rationale and design of the ESMMO trial
    Koonrungsesomboon, Nut
    Ngamphaiboon, Nuttapong
    Townamchai, Natavudh
    Teeyakasem, Pimpisa
    Charoentum, Chaiyut
    Charoenkwan, Pimlak
    Natesirinilkul, Rungrote
    Sathitsamitphong, Lalita
    Ativitavas, Touch
    Chaiyawat, Parunya
    Klangjorhor, Jeerawan
    Hongeng, Suradej
    Pruksakorn, Dumnoensun
    BMC CANCER, 2020, 20 (01)
  • [30] Phase II, multi-center, open-label, single-arm clinical trial evaluating the efficacy and safety of Mycophenolate Mofetil in patients with high-grade locally advanced or metastatic osteosarcoma (ESMMO): rationale and design of the ESMMO trial
    Nut Koonrungsesomboon
    Nuttapong Ngamphaiboon
    Natavudh Townamchai
    Pimpisa Teeyakasem
    Chaiyut Charoentum
    Pimlak Charoenkwan
    Rungrote Natesirinilkul
    Lalita Sathitsamitphong
    Touch Ativitavas
    Parunya Chaiyawat
    Jeerawan Klangjorhor
    Suradej Hongeng
    Dumnoensun Pruksakorn
    BMC Cancer, 20
12345