COMPARATIVE ANTIMICROBIAL ANALYSIS OF GREEN SYNTHESIZED SILVER NANOPARTICLES USING BERBERIS LYCIUM ROOT EXTRACTS AND BERBERINE

Due to their significant biological potential, nanoparticles have been a focus of recent research. For the synthesis of the silver nanoparticles, pure berberine and aqueous root extracts of Berberis lycium were employed. Analytical methods like UV-Visible spectroscopy, FT-IR, SEM, and XRD were used to characterize the nanoparticles' structural and functional properties. The particles were spherical in shape with an average crystal size of Berberine AgNPs 47nm and of B. lycium root extract AgNPs was 16nm. MIC of B. lycium root extract AgNps was 1.5 & mu;g/ml with IC50 of 2.463 and MIC of berberine AgNps was 2.5 & mu;g/ml and IC50 of 2.599 against E. coli. MIC of B. lycium root extract AgNps was 1.5 & mu;g/ml and IC50 of 2. 514 and MIC of berberine AgNps was 1.5 & mu;g/ml and IC50 of 2.922 against S. aureus. The nanoparticles synthesized with root extracts were found to be more potent as antibacterial agents.