SIMPLE AND EFFICIENT GREEN METHODS INVOLVING MICROWAVES AND MECHANOCHEMISTRY FOR SYNTHESIS OF A SCHIFF LIGAND, 3, 3'-([1,1'-BIPHENYL]-4,4'- DIYLBIS(AZANYLYLIDENE))BIS(INDOLIN-2-ONE) WITH ANTIMICROBIAL ACTIVITY

被引：0
作者：
Bratulescu, George [1 ]
机构：
[1] Univ Craiova, Fac Sci, Dept Chem, 13 AI Cuza St, Craiova 200585, Romania
来源：
FARMACIA | 2023年 / 71卷 / 01期
关键词：
isatin; Schiff base; mechanochemistry; microwaves; structural analysis; antibacterial and antifungal activity; SOLVENT-FREE SYNTHESIS; BASE COMPLEXES; ANTIVIRAL ACTIVITY; ANTIBACTERIAL; ANTIFUNGAL;
D O I：
10.31925/farmacia.2023.1.14
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
An azomethine organic ligand was obtained. The synthesis of 3'-([1,1'-biphenyl]-4,4'-diylbis(azanylylidene))bis(indolin-2-one) was accomplished by conventional and green protocols. Three methods have been implemented to obtain the compound. The ligand structure was established by NMR spectra, IR spectrum, UV-vis spectrum and elemental analysis. The comparative study of the experimental protocols was performed. The compound has antibacterial and antifungal activity.
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页码：109 / 115
页数：7
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