Investigating the Electrochemical Properties of Alkaloids Compound Derived from Catharanthus Roseus Extract

The preparation of nanomaterials from organic materials has great interest since they are available, low-cost, and have no poisonous effect in comparison with chemical nanomaterials. Such materials have importance in biological applications. The pure Chitosan, Chitosan nanoparticles, and CSNPs- Linker-alkaloids compound were characterized by X-ray diffractometer, and Fourier Transform Infrared spectroscopy. X-ray results show that all samples have an orthorhombic structure with crystallite size in the nanoscale. Fourier transform infrared (FTIR) spectra of Chitosan nanoparticles proved that the P=O is the cross-linkage between chitosan and STPP by ionic bonds, which indicates that chitosan nanoparticles have been formed in the solution. FTIR spectrum of the CSNPs-linker-alkaloids compound showed a new distinct band at 1708.93 cm-1, demonstrating the presence of C = O esterification. Atomic Force Microscope images of chitosan nanoparticles and CSNPs-linker-alkaloids showed that they have almost spherical shapes with average sizes of 90 and 92.6 nm, respectively. CSNPs-linker-alkaloids have a zeta potential of 54.4 mV, which means that this compound has long-term stability. The NPs upgrade the efficiency of modified GCE, where it was noted that the surface area increased by two and three folds compared with that of GCE and extract plant. The successful synthesis of organic nanoparticles from the Catharanthus roseus plant can be used safely in biosensors, environmental monitoring, and biomedical applications.