Langerhans Cell Histiocytosis Showed Intense Uptake of 68Ga-FAPI

被引：4

作者：

Pan, Qingqing ^{[1
,2
]}

Zhang, Hongzhe ^{[1
,2
]}

Cao, Xinxin ^{[3
]}

Li, Jian ^{[3
]}

Luo, Yaping ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Dept Nucl Med, 1 Shuaifuyuan Wangfujing, Beijing 100730, Peoples R China

[2] Beijing Key Lab Mol Targeted Diag & Therapy Nucl M, Beijing, Peoples R China

[3] Chinese Acad Med Sci & Peking Union Med Coll Hosp, Dept Hematol, Beijing, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2023年 / 48卷 / 10期

基金：

北京市自然科学基金;

关键词：

Langerhans cell histiocytosis; Ga-68-FAPI; PET/CT;

D O I：

10.1097/RLU.0000000000004786

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 23-year-old man was recently diagnosed with Langerhans cell histiocytosis (LCH). 68Ga-FAPI PET/CT showed multiple lesions with intense FAPI uptake in the axial and appendicular skeleton with lytic or mixed bone destruction, consistent with osseous lesions of LCH. FAPI-avid foci around the right atrium and inferior vena cava, as well as micronodules and thin-walled cysts in the lungs, were also noted, possibly also involvement of LCH. This case suggested that 68Ga-FAPI PET/CT may have the potential to be applied in evaluation of LCH. © Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：894 / 895

页数：2

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