THE EFFECTS OF UPADACITINIB ON ULCERATIVE COLITIS SYMPTOM RESOLUTION AND FATIGUE NORMALIZATION IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: PHASE 3 U-ACHIEVE AND U-ACCOMPLISH RESULTS

被引：0
|
作者：
D'Haens, Geert
Tran, Jacinda N.
Danese, Silvio
Rubin, David T.
Aoyama, Nobuo
Lugering, Andreas
Klaff, Justin
Xuan, Si
Ilo, Dapo
Gonzalez, Yuri Sanchez
Panes, Julian
机构：
来源：
GASTROENTEROLOGY | 2023年 / 164卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
Tu1737
引用
收藏
页码：S1102 / S1103
页数：2
相关论文
共 50 条
  • [31] Maintenance of health-related quality of life improvements with upadacitinib treatment among patients with moderately to severely active ulcerative colitis: results from, 52-week phase, 3 study U ACHIEVE maintenance
    Panes, J.
    Loftus, E. V. J.
    Higgins, P.
    Lindsay, J. O.
    Zhou, W.
    Yao, X.
    Ilo, D.
    Phillips, C.
    Tran, J.
    Sanchez Gonzalez, Y.
    Vermeire, S.
    JOURNAL OF CROHNS & COLITIS, 2022, 16 : I373 - I374
  • [32] Maintenance of health-related quality of life improvements with upadacitinib treatment among patients with moderately to severely active ulcerative colitis: results from, 52-week phase, 3 study U ACHIEVE maintenance
    Panes, J.
    Loftus, E. V. J.
    Higgins, P.
    Lindsay, O.
    Zhou, W.
    Yao, X.
    Ilo, D.
    Phillips, C.
    Tran, J.
    Gonzalez, Y. Sanchez
    Vermeire, S.
    JOURNAL OF CROHNS & COLITIS, 2022, 16 : I373 - I374
  • [33] Upadacitinib modulates inflammatory pathways in gut tissue in patients with Ulcerative Colitis: Transcriptomic profiling from the Phase 2b study, U-ACHIEVE
    Verstockt, B.
    Polakow, S. Blink
    Mahi, N.
    Lee, J.
    Wang, J.
    Guay, H.
    Salas, A.
    Panes, J.
    Ungaro, R. C.
    Vermeire, S.
    JOURNAL OF CROHNS & COLITIS, 2022, 16 : I033 - I034
  • [34] Identification of biomarkers and mechanistic insight for upadacitinib in ulcerative colitis: Analysis of serum inflammatory mediators in the phase 2b U-ACHIEVE study
    Vermeire, S.
    Guay, H.
    Verstockt, B.
    Fann, J.
    Cheng, J.
    Hong, F.
    Lee, W. J.
    Lacerda, A.
    Zhou, W.
    Danese, S.
    JOURNAL OF CROHNS & COLITIS, 2020, 14 : S057 - S058
  • [35] Efficacy and safety of upadacitinib maintenance therapy for moderately to severely active ulcerative colitis in patients responding to 8 week induction therapy (U-ACHIEVE Maintenance): overall results from the randomised, placebo-controlled, double-blind, phase 3 maintenance study
    Vermeire, Severine
    Danese, Silvio
    Zhou, Wen
    Ilo, Dapo
    Klaff, Justin
    Levy, Gweneth
    Yao, Xuan
    Chen, Su
    Gonzalez, Yuri Sanchez
    Hebuterne, Xavier
    Lindsay, James
    Higgins, Peter D. R.
    Cao, Qian
    Nakase, Hiroshi
    Colombel, Jean-Frederic
    Loftus, Edward V., Jr.
    Panaccione, Remo
    LANCET GASTROENTEROLOGY & HEPATOLOGY, 2023, 8 (11): : 976 - 989
  • [36] IDENTIFICATION OF BIOMARKERS AND MECHANISTIC INSIGHT FOR UPADACITINIB IN ULCERATIVE COLITIS: ANALYSIS OF SERUM INFLAMMATORY MEDIATORS IN THE PHASE 2B U-ACHIEVE STUDY
    Vermeire, Severine
    Guay, Heath M.
    Verstockt, Bram
    Fann, James
    Cheng, Jie
    Hong, Feng
    Lee, Wan-Ju
    Lacerda, Ana P.
    Zhou, Wen
    Danese, Silvio
    GASTROENTEROLOGY, 2020, 158 (06) : S1197 - S1197
  • [37] Guselkumab improves symptoms of fatigue in patients with moderately to severely active Ulcerative Colitis: Phase 3 QUASAR induction study results at Week 12
    Dignass, A.
    Panes, J.
    Rubin, D. T.
    Huang, K. H. G.
    Germinaro, M.
    Pandya, D.
    Han, C.
    Miao, Y.
    Zhang, H.
    Gu, F.
    Rowbotham, D.
    Mihaly, E.
    Bressler, B.
    Lichtenstein, G. R.
    Allegretti, J. R.
    JOURNAL OF CROHNS & COLITIS, 2024, 18 : I165 - I166
  • [38] GUSELKUMAB IMPROVES SYMPTOMS OF FATIGUE IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: PHASE 3 QUASAR INDUCTION STUDY RESULTS AT WEEK 12
    Dignass, Axel
    Panes, Julian
    Rubin, David T.
    Huang, Kuan-Hsiang G.
    Germinaro, Matthew
    Pandya, Dwiti
    Han, Chenglong
    Miao, Ye
    Zhang, Hongyan
    Gu, Fang
    Rowbotham, David S.
    Mihaly, Emese
    Bressler, Brian
    Lichtenstein, Gary R.
    Allegretti, Jessica R.
    GASTROENTEROLOGY, 2024, 166 (05) : S848 - S849
  • [39] Benefits of High versus Low Dose Upadacitinib as Maintenance Treatment in Ulcerative Colitis Patients Who Were Responders to 8-week Induction with Upadacitinib: Results From the U-ACHIEVE Phase 3 Maintenance Trial
    Feagan, Brian G.
    Parkes, Gareth
    Juillerat, Pascal
    Gecse, Krisztina
    Yao, Xuan
    Zhou, Wen
    Deng, Huiwen
    Ilo, Dapo
    Sanchez-Gonzalez, Yuri
    Higgins, Peter D.
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2022, 117 (10): : S496 - S496
  • [40] Induction and Maintenance Treatment With Upadacitinib Improves Health-Related Quality of Life in Patients With Moderately to Severely Active Ulcerative Colitis: Phase 3 Study Results
    Panes, Julian
    Loftus, Edward, V
    Higgins, Peter D. R.
    Lindsay, James O.
    Zhou, Wen
    Yao, Xuan
    Ilo, Dapo
    Phillips, Charles
    Tran, Jacinda
    Sanchez Gonzalez, Yuri
    Vermeire, Severine
    INFLAMMATORY BOWEL DISEASES, 2023, : 1421 - 1430
12345