Efficacy of Intranasal Atomized Dexmedetomidine for Sedation in Surgical Removal of Impacted Mandibular Third Molars: A Prospective Study

被引:1
作者
Bhargavi, Marupaka [1 ]
Sarath, Gangisetty Sai [1 ]
Surana, Pratik [2 ]
Dhull, Kanika S. [3 ]
Shaikh, Maheen [4 ]
Rajan, Milino [5 ]
机构
[1] Panineeya Inst Dent Sci & Res Ctr, Dept Oral & Maxillofacial Surg, Hyderabad, India
[2] Maitri Coll Dent & Res Ctr, Dept Pedodont & Prevent Dent, Durg, India
[3] Kalinga Inst Dent Sci, Dept Pedodont & Prevent Dent, Bhubaneswar, India
[4] M A Rangoonwala Coll Dent Sci & Res Ctr, Dept Pedodont & Prevent Dent, Pune, India
[5] M A Rangoonwala Coll Dent Sci & Res Ctr, Dept Pediat & Prevent Dent, Pune, India
关键词
impacted mandibular third molars; surgical removal; sedation; atomized dexmedetomidine; intranasal; ANESTHESIA; CHILDREN; SURGERY; SAFETY;
D O I
10.7759/cureus.36721
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Aims and objectives: To assess the efficacy of dexmedetomidine atomized intranasally for sedation during surgical removal of impacted mandibular third molars. Materials and methods: A prospective randomized trial was conducted on 25 anxious patients between the ages of 18 and 40 who had impacted the lower third molars. An intranasal atomization device was used to give the medication 30 minutes prior to the surgical procedure. The Ramsay sedation score and Observer???s assessment of alertness/sedation score were used to assess intranasal sedation. Results: The results of our study state that the sedative effect began to take effect between 30 and 45 minutes later and was nearly back to baseline by 105 minutes after the administration of intranasal dexmedetomidine. Conclusion: Intranasal delivery of 1.5mg/kg atomized dexmedetomidine for patients undergoing surgical removal of impacted mandibular third teeth is safe, feasible, and clinically efficient in daycare settings based on the sedation scores, and secondary variables which were assessed.
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页数:9
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