ASO Author Reflections: A Multiomic Novel Staging System for Esophageal Squamous Cell Carcinoma Patients

被引：1

作者：

Zheng, Shao-Jun ^{[1
]}

Li, En-Min ^{[1
]}

Xu, Li-Yan ^{[1
]}

机构：

[1] Shantou Univ, Med Coll, Inst Oncol Pathol, Canc Res Ctr,Guangdong Prov Key Lab Infect Dis & M, Shantou, Guangdong, Peoples R China

来源：

ANNALS OF SURGICAL ONCOLOGY | 2023年 / 30卷 / 04期

关键词：

D O I：

10.1245/s10434-022-13041-7

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The past eighth edition of the American Joint Committee on Cancer (AJCC)/International Union against Cancer (UICC) pathologic tumor-node-metastasis (pTNM) staging system for esophageal squamous cell carcinoma (ESCC) patients, which also is the gold standard of postoperative treatment decision-making, needs to be continuously improved. To improve the efficiency of the staging system, the proteomic data from Chinese ESCC patients was combined with preoperative radiomic data and pTNM data to establish the multiomic RadpTNM and ProtRadpTNM models and compare them with the traditional pTNM staging system. The results suggest that both the RadpTNM and ProtRadpTNM models are significantly better than the traditional pTNM staging system. Future prospective multicentered cohort studies in Asian and Caucasian patients with ESCC are warranted to evaluate the efficiency of the multiomic models.

引用

页码：2242 / 2243

页数：2

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