A case of comorbidity of schizophrenic catatonia and chronic intestinal pseudo-obstruction Successfully managed with lorazepam

被引:1
作者
Cao, Yang [1 ]
Wang, Weixin [1 ]
Chen, Jiong [1 ]
Jiang, Bo [1 ]
Liang, Sugai [2 ]
Chen, Xianyu [3 ]
Dong, Hui [4 ]
机构
[1] Tongde Hosp Zhejiang Prov, Zhejiang Prov Mental Hlth Inst, Hangzhou, Peoples R China
[2] Zhejiang Univ, Hangzhou Peoples Hosp Hangzhou 7, Affiliated Mental Hlth Ctr, Sch Med, Hangzhou, Peoples R China
[3] Kunming Med Univ, Affiliated Hosp 1, Psychiat Dept, Kunming, Peoples R China
[4] Zhejiang Hosp, Gastroenterol Dept, Hangzhou, Peoples R China
关键词
Catatonia; Chronic intestinal pseudo-obstruction; Schizophrenia; Treatment; Lorazepam; Gamma-aminobutyric acid; RECEPTORS; BENZODIAZEPINE; ORGANIZATION; DIAGNOSIS; GLUTAMATE; NUCLEUS;
D O I
10.1016/j.heliyon.2023.e21067
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
It is challenging to manage schizophrenic catatonia and comorbid chronic intestinal pseudoobstruction (CIPO). The pathology of catatonia is unclear. There are few reports or research on this issue. In this case, we present a middle-aged woman diagnosed with schizophrenia with catatonic features and comorbid CIPO. In the treatment process, modified electroconvulsive therapy (mECT) improved her stupor and CIPO partially. Lorazepam alleviated her stupor and CIPO completely. It is the first report describing complete remission with lorazepam in patient suffering from comorbid schizophrenic catatonia and CIPO, which may benefit the exploration of pathophysiology and treatment of comorbidity of schizophrenia with catatonia and CIPO.
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页数:8
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