Advancing full-field metrology: rapid 3D imaging with geometric phase ferroelectric liquid crystal technology in full-field optical coherence microscopy

被引:1
|
作者
Zheng, Wei [1 ]
Kou, Shan S. [2 ]
Sheppard, Colin J. R. [3 ,4 ]
Roy, Maitreyee [5 ]
机构
[1] Natl Univ Singapore, Dept Biomed Engn, Singapore 117576, Singapore
[2] La Trobe Univ, Chem & Phys, Bundoora, Vic 3083, Australia
[3] Ist Italiano Tecnol, Nanoscopy & NIC IIT, Via Enrico Melen,83 Edificio B, I-16152 Genoa, Italy
[4] Univ Wollongong, Sch Chem & Mol Biosci, Mol Horizons, Wollongong, NSW 2522, Australia
[5] Univ New South Wales, Sch Optometry & Vis Sci, Sydney, NSW 2052, Australia
关键词
CONFOCAL INTERFERENCE MICROSCOPE; WHITE-LIGHT INTERFEROMETRY; DOMAIN REFLECTOMETRY; SCANNING MICROSCOPY; AXIAL RESOLUTION; SCATTERING; TOMOGRAPHY; HETERODYNE; REFLECTION; RECONSTRUCTION;
D O I
10.1364/BOE.488806
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Optical coherence microscopy (OCM) is a variant of OCT in which a high-numerical aperture lens is used. Full-field OCM (FF-OCM) is an emerging non-invasive, label-free, interferometric technique for imaging of surface structures or semi-transparent biomedical subjects with micron-scale resolutions. Different approaches to three dimensional full-field optical metrology are reviewed. The usual method for the phase-shifting technique in FF-OCM involves mechanically moving a mirror to change the optical path difference for obtaining en-face OCM images. However, with the use of a broadband source in FF-OCM, the phase shifts of different spectral components are not the same, resulting in the ambiguities in 3D image reconstruction. In this study, we demonstrate, by imaging tissues and cells, a unique geometric phase-shifter based on ferroelectric liquid crystal technology, to realize achromatic phase-shifting for rapid three-dimensional imaging in a FF-OCM system.
引用
收藏
页码:3433 / 3445
页数:13
相关论文
共 50 条
  • [1] Full-field optical coherence microscopy
    Cent Natl de la Recherche, Paris, France
    Opt Lett, 4 (244-246):
  • [2] Full-field optical coherence microscopy
    Beaurepaire, E
    Boccara, AC
    Lebec, M
    Blanchot, L
    Saint-Jalmes, H
    OPTICS LETTERS, 1998, 23 (04) : 244 - 246
  • [3] Full-field optical coherence microscopy
    Dubois, A
    Grieve, K
    Moneron, G
    Boccara, AC
    ALT'03 INTERNATIONAL CONFERENCE ON ADVANCED LASER TECHNOLOGIES: BIOMEDICAL OPTICS, 2003, 5486 : 107 - 111
  • [4] Retinal imaging with full-field optical coherence microscopy
    Grieve, Kate
    Borderie, Vincent
    Paques, Michel
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2016, 57 (12)
  • [5] Extended Full-field Optical Coherence Microscopy
    Dubois, Arnaud
    3RD INTERNATIONAL TOPICAL MEETING ON OPTICAL SENSING AND ARTIFICIAL VISION (OSAV'2012), 2013, 1537 : 123 - 132
  • [6] Bichromatic tetraphasic full-field optical coherence microscopy
    Iyer, Rishyashring R.
    Zurauskas, Mantas
    Rao, Yug
    Chaney, Eric J.
    Boppart, Stephen A.
    JOURNAL OF BIOMEDICAL OPTICS, 2024, 29
  • [7] Full-field optical coherence tomography for rapid 3-D imaging in biological systems
    Zheng, Wei
    Sheppard, Colin J. R.
    OPTICAL COHERENCE TOMOGRAPHY AND COHERENCE DOMAIN OPTICAL METHODS IN BIOMEDICINE XV, 2011, 7889
  • [8] Combined full-field fluorescence and optical coherence microscopy
    Perronet, K.
    Makhlouf, H.
    Dubois, A.
    EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS, 2013, 42 : S104 - S104
  • [9] Full-field optical coherence tomography for tissue imaging
    Dubois, A.
    BIOPHOTONICS SOUTH AMERICA, 2015, 9531
  • [10] Full-Field Optical Coherence Tomography: A New Technology for 3D High-Resolution Skin Imaging
    Dalimier, Eugenie
    Salomon, Denis
    DERMATOLOGY, 2012, 224 (01) : 84 - 92