Heat Transfer Capabilities of Surface Cooling Systems for Inducing Therapeutic Hypothermia

被引:1
作者
Leclerc, Curtis [1 ]
Nia, Morteza Talebian [1 ]
Giesbrecht, Gordon G. [1 ,2 ,3 ]
机构
[1] Univ Manitoba, Fac Kinesiol & Recreat Management, Winnipeg, MB, Canada
[2] Univ Manitoba, Fac Med, Dept Anesthesia, Winnipeg, MB, Canada
[3] Univ Manitoba, Fac Med, Dept Emergency Med, Winnipeg, MN, Canada
基金
加拿大自然科学与工程研究理事会;
关键词
cerebral ischemia; hypothermia; skin cooling; CARDIAC-ARREST; CARDIOPULMONARY-RESUSCITATION; BRAIN TEMPERATURE; DOWN-REGULATION; GUIDELINES; ISCHEMIA; CARE;
D O I
10.1089/ther.2023.0003
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Therapeutic hypothermia (TH) is used to treat patients with cerebral ischemia. Body surface cooling provides a simple noninvasive method to induce TH. We compared three surface cooling systems (Arctic Sun with adhesive ArcticGel pads [AS]); Blanketrol III with two nonadhesive Maxi-Therm Lite blankets [BL]); and Blanketrol III with nonadhesive Kool Kit [KK]). We hypothesized that KK would remove more heat due to its tighter fit and increased surface area. Eight subjects (four females) were cooled with each system set to 4 degrees C outflow temperature for 120 minutes. Heat loss, skin and esophageal temperature, and metabolic heat production were measured. Skin temperature was higher with KK (p = 0.002), heat loss was lower with KK in the first hour (p = 0.014) but not after 120 minutes. Heat production increased similarly with all systems. Core temperature decrease was greater for AS (0.57 degrees C) than BL (0.14 degrees C; p = 0.035), but not KK (0.24 degrees C; p = 0.1). Each system had its own benefits and limitations. Heat transfer capability is dependent on the cooling pump unit and the design of the liquid-perfused covers. Both Arctic Sun and Blanketrol III cooling/pump units had 4 degrees C output temperatures. However, the Blanketrol III unit had a greater flow rate and therefore more cooling power. The nonadhesive BL and KK covers were easier to apply and remove compared with the adhesive AS pads. AS had an early transient advantage in heat removal, but this effect decreased over the course of cooling, thus minimizing or eliminating any advantage during longer periods of cooling that occur during clinical TH.Clinical Trial Registration number: NCT04332224.
引用
收藏
页码:149 / 158
页数:10
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