Mental navigation and the neural mechanisms of insight

被引：11

作者：

Aru, Jaan ^{[1
]}

Drueke, Moritz ^{[2
]}

Pikamae, Juhan ^{[3
]}

Larkum, Matthew E. ^{[2
,4
]}

机构：

[1] Univ Tartu, Inst Comp Sci, Tartu, Estonia

[2] Humboldt Univ, Inst Biol, Berlin, Germany

[3] Univ Tartu, Inst Mol & Cell Biol, Tartu, Estonia

[4] Charite Univ Med Berlin, Neurocure Ctr Excellence, Berlin, Germany

来源：

TRENDS IN NEUROSCIENCES | 2023年 / 46卷 / 02期

基金：

欧盟地平线“2020”;

关键词：

COMPLEMENTARY LEARNING-SYSTEMS; CELLULAR MECHANISM; DECLARATIVE MEMORY; UNIT-ACTIVITY; SPATIAL MAP; PLACE CELLS; HIPPOCAMPUS; NEOCORTEX; REPRESENTATION; DENDRITES;

D O I：

10.1016/j.tins.2022.11.002

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

How do new ideas come about? The central hypothesis presented here states that insights might happen during mental navigation and correspond to rapid plasticity at the cellular level. We highlight the differences between neocortical and hippocampal mechanisms of insight. We argue that the suddenness of insight can be related to the sudden emergence of place fields in the hippocampus. According to our hypothesis, insights are supported by a state of mind-wandering that can be tied to the process of combining knowledge pieces during sharp-wave ripples (SWRs). Our framework connects the dots between research on creativity, mental navigation, and specific synaptic plasticity mechanisms in the hippocampus.

引用

页码：100 / 109

页数：10

共 104 条

[31] Manipulating Hippocampal Place Cell Activity by Single-Cell Stimulation in Freely Moving Mice [J].