A Modular and Cost-Effective Droplet Microfluidic Device for Controlled Emulsion Production

被引：0
|
作者：
Jiang, Hao [1 ]
Liu, Zhaoyue [1 ]
Tang, Fengwei [1 ]
Cheng, Yimin [1 ]
Tian, Wei [1 ]
Shi, Woda [2 ]
Zhang, Jia Ming [1 ,3 ]
Zhang, Yajun [2 ]
机构：
[1] Nanjing Univ Aeronaut & Astronaut, Coll Mech & Elect Engn, Nanjing 210016, Peoples R China
[2] Nanjing Med Univ, Affiliated Hosp 6, Yancheng Peoples Hosp 3, Dept Cardiothorac Surg,Yancheng Sch Clin Med,Nanto, Yancheng 224000, Peoples R China
[3] Yangtze River Delta Intelligent Mfg Innovat Ctr, Nanjing 210014, Peoples R China
来源：
POLYMERS | 2024年 / 16卷 / 06期
关键词：
droplet; modular; cost-effective; emulsion; microfluidics; CHIPS;
D O I：
10.3390/polym16060765
中图分类号：
O63 [高分子化学（高聚物）];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
The droplet microfluidic device has become a widely used tool in fields such as physics, chemistry, and biology, but its complexity has limited its widespread application. This report introduces a modular and cost-effective droplet microfluidic device for the controlled production of complex emulsions, including oil and aqueous single emulsions, and double emulsions with varying numbers of encapsulated droplets. The droplet sizes can be precisely controlled by easily replacing flat needles and adjusting the needle position within an axially accelerated co-flow field. This modular device not only allows for easy repair and maintenance in case of device clogging or damage but can also be readily expanded to produce complex emulsions. The low-cost and user-friendly nature of the device greatly facilitates the widespread adoption and utilization of droplet microfluidics.
引用
收藏
页数：11
相关论文
共 50 条
  • [41] Microfluidic channels laser-cut in thin double-sided tapes: Cost-effective biocompatible fluidics in minutes from design to final integration with optical biochips
    Patko, Daniel
    Martonfalvi, Zsolt
    Kovacs, Boglarka
    Vonderviszt, Ferenc
    Kellermayer, Miklos
    Horvath, Robert
    SENSORS AND ACTUATORS B-CHEMICAL, 2014, 196 : 352 - 356
  • [42] Cost-effective track and trace technology for poor-quality chemotherapeutic pharmaceuticals in resource-limited countries: a review of the Chemotherapeutic Paper Analytical Device
    Worku, Minichil Chanie
    Limenh, Liknew Workie
    Mekonnen, Biset Asrade
    Anagaw, Yeniewa Kerie
    FRONTIERS IN MEDICAL TECHNOLOGY, 2024, 6
  • [43] Cost-effective synthesis of carbon loaded Co3O4 for controlled hydrogen generation via NaBH4 hydrolysis
    Ugale, Ashok D.
    Ghodke, Neha P.
    Kang, Gil-Seon
    Nam, Ki-Bong
    Bhoraskar, Sudha, V
    Mathe, Vikas L.
    Yoo, Ji Beom
    INTERNATIONAL JOURNAL OF HYDROGEN ENERGY, 2022, 47 (01) : 16 - 29
  • [44] Combination of utilization of CO2 from flue gas of biomass power plant and medium recycling to enhance cost-effective Spirulina production
    Huijun Cui
    Zihan Yang
    Zhe Lu
    Qishuo Wang
    Jin Liu
    Lirong Song
    Journal of Applied Phycology, 2019, 31 : 2175 - 2185
  • [45] Combination of utilization of CO2 from flue gas of biomass power plant and medium recycling to enhance cost-effective Spirulina production
    Cui, Huijun
    Yang, Zihan
    Lu, Zhe
    Wang, Qishuo
    Liu, Jin
    Song, Lirong
    JOURNAL OF APPLIED PHYCOLOGY, 2019, 31 (04) : 2175 - 2185
  • [46] One-Step Production Using a Microfluidic Device of Highly Biocompatible Size-Controlled Noncationic Exosome-like Nanoparticles for RNA Delivery
    Kimura, Niko
    Maeki, Masatoshi
    Ishida, Akihiko
    Tani, Hirofumi
    Tokeshi, Manabu
    ACS APPLIED BIO MATERIALS, 2021, 4 (02): : 1783 - 1793
  • [47] Cost-effective activated carbon (AC) production from partial substitution of coal with red mud (RM) as additive for SO2 and NOx abatement at low temperature
    Niu, Jian
    Zhang, Huirong
    Li, Linbo
    Guo, Yanxia
    FUEL, 2021, 293
  • [48] Recirculating coking by-products and waste for cost-effective activated carbon (AC) production and its application for treatment of SO2 and wastewater in coke-making plant
    Zhang, Huirong
    Niu, Jian
    Guo, Yanxia
    Cheng, Fangqin
    JOURNAL OF CLEANER PRODUCTION, 2021, 280
  • [49] Origami chips: Development and validation of a paper-based Lab-on-a-Chip device for the rapid and cost-effective detection of 4-methylmethcathinone (mephedrone) and its metabolite, 4-methylephedrine in urine
    McNeill, Lauren
    Pearson, Catherine
    Megson, David
    Norrey, John
    Watson, Danielle
    Ashworth, David
    Linton, Patricia E.
    Sutcliffe, Oliver B.
    Shaw, Kirsty J.
    FORENSIC CHEMISTRY, 2021, 22
  • [50] Microfluidic devices in diagnostics: what does the future hold? "Key to enabling early disease detection is the availability of diagnostic and prognostic biomarkers, as well as of adequate technologies that enable cost-effective diagnostics, discovery and large-scale population screening applications."
    Lazar, Iulia M.
    BIOANALYSIS, 2015, 7 (20) : 2677 - 2680
12345