Nitration of Pyrrolo[2,1-a]isoquinolines

被引：10

作者：

Chen, Xiao-Hui ^{[1
]}

Ma, Dan-Dan ^{[1
,2
]}

Gao, Xin ^{[1
]}

Li, Yun-Meng ^{[1
]}

Jiang, Da-Bo ^{[1
]}

Ma, Chao ^{[2
]}

Cui, Hai-Lei ^{[1
]}

机构：

[1] Chongqing Univ Arts & Sci, Chongqing 402160, Peoples R China

[2] Hubei Univ, Coll Chem & Chem Engn, Wuhan 430062, Hubei, Peoples R China

来源：

JOURNAL OF ORGANIC CHEMISTRY | 2023年 / 88卷 / 07期

基金：

中国国家自然科学基金;

关键词：

C-H NITRATION; CERIUM(IV) AMMONIUM-NITRATE; BOND NITRATION; FUNCTIONALIZATION; ALKALOIDS; 8-AMINOQUINOLINES; LAMELLARINS; CONVERSION; INDOLINES; EFFICIENT;

D O I：

10.1021/acs.joc.3c00125

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

We have successfully modified a series of pyrrolo[2,1-a]isoquinolines via direct nitration under mild reaction conditions. Easily accessible nitrates including CAN, Cu(NO3)2 center dot H2O, and Fe(NO3)3 center dot 9H2O all can serve as effective nitrating reagents for functionalizing pyrrolo[2,1-a]isoquinolines. Various nitro-bearing pyrrolo[2,1-a]isoquinolines have been efficiently prepared in acceptable to good yields.

引用

页码：4649 / 4661

页数：13

共 50 条

[1] Nitration of Pyrrolo[2,1-a]isoquinolines with NaNO2/HFIP
Huang, Xiang
Li, Yun-Meng
Zhou, Jing
Pan, Yu-Yi
Li, Wei
Chen, Xiao-Hui
Yu, Xin
Pei, Shu-Chen
Cui, Hai-Lei
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 27 (16)
[2] Recent progress in the synthesis of pyrrolo[2,1-a]isoquinolines
Cui, Hai-Lei
ORGANIC & BIOMOLECULAR CHEMISTRY, 2022, 20 (14) : 2779 - 2801
[3] Iron-catalyzed dimerization of pyrrolo[2,1-a]isoquinolines and pyrrolo [1,2-a]quinolines
Huang, Xiang
Li, Wan-Zhen
Pei, Shu-Chen
Cui, Hai -Lei
TETRAHEDRON LETTERS, 2023, 126
[4] AcBr/DMSO Mediated Sulfenylation of Pyrrolo[2,1-a]isoquinolines
Chen, Xiao-Hui
Cui, Hai-Lei
JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (11) : 7347 - 7361
[5] Bromination of Pyrrolo[2,1-a]isoquinolines with Acetyl Bromide and Dimethyl Sulfoxide
Cui, Hai-Lei
JOURNAL OF ORGANIC CHEMISTRY, 2023, 88 (05) : 2822 - 2831
[6] A facile synthesis of 1-oxo-pyrrolo[2,1-a]isoquinolines
Voskressensky, Leonid G.
Borisova, Tatiana N.
Matveeva, Maria D.
Khrustalev, Viktor N.
Titov, Alexander A.
Aksenov, Alexander V.
Dyachenko, Svetlana V.
Varlamov, Alexey V.
TETRAHEDRON LETTERS, 2017, 58 (09) : 877 - 879
[7] HI/DMSO-Based Chemoselective Oxidative Halogenation of Pyrrolo[2,1-a ]isoquinolines
Cui, Hai-Lei
SYNLETT, 2025,
[8] Green production and antioxidant activity study of new pyrrolo[2,1-a]isoquinolines
Amiri, Somayeh Soleimani
JOURNAL OF HETEROCYCLIC CHEMISTRY, 2020, 57 (11) : 4057 - 4069
[9] HBr/TMSO/HFIP Mediated Chemoselective Modifications of Pyrrolo[2,1-a]Isoquinolines
Li, Yun-Meng
Jiang, Man
Zhou, Jing
Cui, Hai-Lei
ASIAN JOURNAL OF ORGANIC CHEMISTRY, 2024, 13 (11)
[10] TBHP/Et3N-Promoted Chemoselective Formylation and Peroxidation of Pyrrolo[2,1-a]isoquinolines
Huang, Xiang
Zhou, Jing
Pei, Shu-Chen
Cui, Hai-Lei
JOURNAL OF ORGANIC CHEMISTRY, 2024, 89 (09) : 6353 - 6363

← 1 2 3 4 5 →