Sustained increase of paediatric invasive Streptococcus pyogenes infections dominated by M1UK and diverse emm12 isolates, Portugal, September 2022 to May 2023

被引：43

作者：

Gouveia, Catarina ^{[1
]}

Bajanca-Lavado, Maria Paula ^{[2
]}

Mamede, Rafael ^{[3
]}

Carvalho, Ana Araujo ^{[1
]}

Rodrigues, Fernanda ^{[4
]}

Melo-Cristino, Jose ^{[3
]}

Ramirez, Mario ^{[3
]}

Friaes, Ana ^{[3
]}

机构：

[1] Ctr Hosp Univ Lisboa Cent, Hosp Dona Estefania, Pediat Dept, Infect Dis Unit, Lisbon, Portugal

[2] Inst Nacl Saude Dr Ricardo Jorge, Dept Doencas Infeciosas, Lab Nacl Referencia Infecoes Resp & Agentes Bacte, Lisbon, Portugal

[3] Univ Lisbon, Inst Microbiol, Inst Med Mol, Fac Med, Lisbon, Portugal

[4] Ctr Hosp Univ Coimbra, Hosp Pediat, Coimbra, Portugal

来源：

EUROSURVEILLANCE | 2023年 / 28卷 / 36期

关键词：

D O I：

10.2807/1560-7917.ES.2023.28.36.2300427

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Since autumn 2022, observed numbers of paediatric invasive group A Streptococcus infections in Portugal (n = 89) were higher than in pre-COVID-19 seasons. Between September 2022 and May 2023, the domi-nant diagnoses were pneumonia (25/79), mostly with empyema (20/25), and sepsis (22/79). A number of cases required admission to intensive care (27/79) and surgery (35/79), and the case fatality rate was 5.1% (4/79). Genomic sequencing (n = 55) revealed multiple genetic lineages, dominated by the M1UK sublineage (26/55) and more diverse emm12 isolates (12/55).

引用

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