Two New Anti-Tobacco Mosaic Virus Quinolin-2(1H)-Ones from the Twigs of Cassia auriculata

被引：2

作者：

Zheng, Chao-Pei ^{[1
,2
]}

Xiong, Wen ^{[2
]}

Zhang, Ling-Fang ^{[1
]}

Jin, Wang ^{[2
]}

Zhang, Jian-Duo ^{[2
]}

Li, Yin-Ke ^{[1
,2
]}

Hu, Qiu-Fen ^{[1
,2
]}

Min, Zhou ^{[1
]}

Kong, Guang-Hui ^{[3
]}

Ye, Yan-Qing ^{[1
]}

Wu, Yu-Ping ^{[3
]}

机构：

[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China

[2] China Tobacco Yunnan Ind Co Ltd, Yunnan Key Lab Tobacco Chem, Kunming 650231, Peoples R China

[3] Yunnan Acad Tobacco Agr Sci, Kunming 650031, Peoples R China

来源：

CHEMISTRY OF NATURAL COMPOUNDS | 2023年 / 59卷 / 01期

基金：

中国国家自然科学基金;

关键词：

quinolin-2(1H)-one; Cassia auriculata; anti-tobacco mosaic virus activity; CONSTITUENTS; ALKALOIDS; PRODUCTS; ALATA; SEEDS; LINN;

D O I：

10.1007/s10600-023-03928-6

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new quinolin-2(1H)-ones, 7-methoxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (1) and 7-hydroxy-6-methyl-4-(4-methylfuran-2-yl)quinolin-2(1H)-one (2), were isolated from the twigs of Cassia auriculata. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 exhibited potential anti-TMV activity with inhibition rates of 38.4 and 49.2%, respectively.

引用

页码：107 / 110

页数：4

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