The oligometastatic setting in HNSCC: A critical review by the Rete Oncologica Piemonte e Valle d′Aosta multidisciplinary team

被引:5
作者
Denaro, Nerina [1 ]
Succo, Giovanni [2 ]
Ostellino, Oliviero [3 ]
Airoldi, Mario [3 ]
Merlano, Marco Carlo [4 ]
Badellino, Serena [5 ]
Solinas, Cinzia [6 ]
Garrone, Ornella [1 ]
Iorio, Giuseppe Carlo [5 ]
机构
[1] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Dept Med Oncol, I-20122 Milan, Italy
[2] Univ Turin, Oncol Dept Head & Neck Surg, Turin, Italy
[3] Citt Salute & Sci Torino, Oncol Unit 2, Turin, Italy
[4] FPO IRCCS Candiolo, Candiolo Canc Inst, Sci Direct, I-10060 Turin, Italy
[5] Univ Torino, Dept Oncol, I-10125 Turin, Italy
[6] Policlin Monserrato, Oncol Dept AOU Cagliari, Cagliari, Monserrato, Italy
关键词
SQUAMOUS-CELL CARCINOMA; STEREOTACTIC BODY RADIOTHERAPY; DISTANT METASTASES; PULMONARY METASTASES; NECK-CANCER; RADIATION-THERAPY; SYNCHRONOUS CANCER; F-18-FDG PET/CT; LOCAL TREATMENT; OPEN-LABEL;
D O I
10.1016/j.critrevonc.2023.103968
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Introduction: The oligometastatic disease is a low burden metastatic disease that might still benefit from curable treatment. Squamous cell carcinoma of the head and neck (HNSCC) is a complex group of malignancies, with high rates of loco-regional recurrences. Distant metastases are less frequent, and a single or few deposits are often observed (oligometastatic disease). The optimal management of oligometastatic HNSCC remains to be defined.Materials and methods: Key references were derived from a PubMed query. Hand searching and clinicaltrials.gov were also used.Results: This paper contains a narrative report and a critical discussion of the available evidence on the management of oligometastatic HNSCC patients, with a focus on metastasis-directed therapy (MDT), particularly stereotactic ablative radiotherapy (SABR).Conclusions: in line with literature data, the multidisciplinary evaluation emerged as the key element in the management of oligometastatic HNSCC patients.
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页数:9
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