The role of the endometrial microbiome in embryo implantation and recurrent implantation failur

被引:2
作者
Azar, Pourya Rokhsartalab [1 ]
Karimi, Sarmad [1 ]
Haghtalab, Arian [1 ]
Taram, Saman [1 ]
Hejazi, Milad [1 ]
Sadeghpour, Sonia [2 ,3 ]
Pashaei, Mohammad Reza [4 ]
Ghasemnejad-Berenji, Hojat [2 ]
Taheri-Anganeh, Mortaza [5 ]
机构
[1] Urmia Univ Med Sci, Student Res Comm, Orumiyeh, Iran
[2] Urmia Univ Med Sci, Clin Res Inst, Reprod Hlth Res Ctr, Orumiyeh, Iran
[3] Urmia Univ Med Sci, Sch Med, Dept Obstet & Gynecol, Orumiyeh, Iran
[4] Urmia Univ Med Sci, Sch Med, Dept Internal Med, Orumiyeh, Iran
[5] Urmia Univ Med Sci, Cellular & Mol Med Res Inst, Cellular & Mol Res Ctr, Orumiyeh, Iran
关键词
Endometrial microbiota; Microbiome; Embryo implantation; Recurrent implantation failure; Reproductive outcomes; Infertility; BACTERIAL VAGINOSIS; T-CELLS; PREGNANCY; WOMEN; CYTOKINES; INFLAMMATION; INFERTILITY; ANTIBIOTICS; ASSOCIATION; PROFILE;
D O I
10.1016/j.jri.2024.104192
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There is a suggested pathophysiology associated with endometrial microbiota in cases where repeated implantation failure of high-quality embryos is observed. However, there is a suspected association between endometrial microbiota and the pathogenesis of implantation failure. However, there is still a lack of agreement on the fundamental composition of the physiological microbiome within the uterine cavity. This is primarily due to various limitations in the studies conducted, including small sample sizes and variations in experimental designs. As a result, the impact of bacterial communities in the endometrium on human reproduction is still a subject of debate. In this discourse, we undertake a comprehensive examination of the existing body of research pertaining to the uterine microbiota and its intricate interplay with the process of embryo implantation.
引用
收藏
页数:12
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