The role of the endometrial microbiome in embryo implantation and recurrent implantation failur

被引:2
|
作者
Azar, Pourya Rokhsartalab [1 ]
Karimi, Sarmad [1 ]
Haghtalab, Arian [1 ]
Taram, Saman [1 ]
Hejazi, Milad [1 ]
Sadeghpour, Sonia [2 ,3 ]
Pashaei, Mohammad Reza [4 ]
Ghasemnejad-Berenji, Hojat [2 ]
Taheri-Anganeh, Mortaza [5 ]
机构
[1] Urmia Univ Med Sci, Student Res Comm, Orumiyeh, Iran
[2] Urmia Univ Med Sci, Clin Res Inst, Reprod Hlth Res Ctr, Orumiyeh, Iran
[3] Urmia Univ Med Sci, Sch Med, Dept Obstet & Gynecol, Orumiyeh, Iran
[4] Urmia Univ Med Sci, Sch Med, Dept Internal Med, Orumiyeh, Iran
[5] Urmia Univ Med Sci, Cellular & Mol Med Res Inst, Cellular & Mol Res Ctr, Orumiyeh, Iran
关键词
Endometrial microbiota; Microbiome; Embryo implantation; Recurrent implantation failure; Reproductive outcomes; Infertility; BACTERIAL VAGINOSIS; T-CELLS; PREGNANCY; WOMEN; CYTOKINES; INFLAMMATION; INFERTILITY; ANTIBIOTICS; ASSOCIATION; PROFILE;
D O I
10.1016/j.jri.2024.104192
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
There is a suggested pathophysiology associated with endometrial microbiota in cases where repeated implantation failure of high-quality embryos is observed. However, there is a suspected association between endometrial microbiota and the pathogenesis of implantation failure. However, there is still a lack of agreement on the fundamental composition of the physiological microbiome within the uterine cavity. This is primarily due to various limitations in the studies conducted, including small sample sizes and variations in experimental designs. As a result, the impact of bacterial communities in the endometrium on human reproduction is still a subject of debate. In this discourse, we undertake a comprehensive examination of the existing body of research pertaining to the uterine microbiota and its intricate interplay with the process of embryo implantation.
引用
收藏
页数:12
相关论文
共 50 条
  • [1] Human embryo implantation: The complex interplay between endometrial receptivity and the microbiome
    Peng, Shiyang
    Meri, Amu Qingsan
    Zhou, Min
    Yu, Yuan
    Tian, Dongmei
    Zhu, Shaomi
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2025, 168
  • [2] Characterization of the Endometrial Microbiome in Patients with Recurrent Implantation Failure
    Lozano, Francisca Maria
    Lledo, Belen
    Morales, Ruth
    Cascales, Alba
    Hortal, Monica
    Bernabeu, Andrea
    Bernabeu, Rafael
    MICROORGANISMS, 2023, 11 (03)
  • [3] Understanding the Role of Female Genital Tract Microbiome in Recurrent Implantation Failure
    Lafioniatis, Anastasios
    Samara, Athina A.
    Makaritsis, Peter K.
    Dafopoulos, Stefanos
    Sotiriou, Sotirios
    Dafopoulos, Konstantinos
    JOURNAL OF CLINICAL MEDICINE, 2024, 13 (11)
  • [4] Endometrial fluid biomarkers and their potential as predictors of successful embryo implantation
    Alves, Ana R.
    Dias, Margarida F.
    Silvestre, Margarida
    BIOMEDICINE-TAIWAN, 2023, 13 (03): : 1 - 8
  • [5] Endometrial Factor in Unexplained Infertility and Recurrent Implantation Failure
    Santamaria, Xavier
    Simon, Carlos
    SEMINARS IN REPRODUCTIVE MEDICINE, 2021, 39 (05/06) : 227 - 232
  • [6] Gene profiling reveals the role of inflammation, abnormal uterine muscle contraction and vascularity in recurrent implantation failure
    Dong, Xinyi
    Zhou, Mi
    Li, Xinyu
    Huang, Huijing
    Sun, Yun
    FRONTIERS IN GENETICS, 2023, 14
  • [7] Human implantation: The complex interplay between endometrial receptivity, inflammation, and the microbiome
    Sehring, Jacqueline
    Beltsos, Angeline
    Jeelani, Roohi
    PLACENTA, 2022, 117 : 179 - 186
  • [8] Endometrial immune cell ratios and implantation success in patients with recurrent implantation failure
    Ganeva, Rumiana
    Parvanov, Dimitar
    Vidolova, Nina
    Ruseva, Margarita
    Handzhiyska, Maria
    Arsov, Katarina
    Decheva, Ivon
    Metodiev, Dimitar
    Moskova-Doumanova, Veselina
    Stamenov, Georgi
    JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2023, 156
  • [9] Molecular mechanisms of endometrial embryo implantation
    Schanz A.
    Hess A.
    Shahin A.
    Hirchenhain J.
    Griesinger G.
    Krüssel J.S.
    Der Gynäkologe, 2004, 37 (2): : 123 - 127
  • [10] Chronic endometritis and the endometrial microbiota: implications for reproductive success in patients with recurrent implantation failure
    Zhang, Hong
    Zou, Heng
    Zhang, Chanyu
    Zhang, Shen
    ANNALS OF CLINICAL MICROBIOLOGY AND ANTIMICROBIALS, 2024, 23 (01)