Synthesis and Evaluation of Herbicidal Activity of [4-(2-Nitrobenzyl)piperazin-1-yl](phenyl)methanone Derivatives

被引：1
|
作者：
Liu, N. [1 ]
Han, J. [2 ]
Bai, H. [2 ]
Bai, Z. [2 ]
Wan, Y. [1 ]
Luo, D. [1 ,2 ]
Li, Z. [1 ,2 ]
机构：
[1] Hunan Univ, Coll Biol, Longping Branch, Changsha 410125, Peoples R China
[2] Hunan Acad Agr Sci, Hunan Prov Key Lab Biol & Control Weeds, Changsha 410125, Peoples R China
来源：
RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2023年 / 93卷 / 10期
关键词：
methanone derivatives; piperazine derivatives; herbicidal activity; PIPERAZINE DERIVATIVES; INHIBITORS; DESIGN; AGENTS;
D O I：
10.1134/S1070363223100122
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A series of novel [4-(2-nitrobenzyl)piperazin-1-yl](phenyl)methanone derivatives containing piperazine structures were designed and synthesized. (3,7-Dichloroquinolin-8-yl)[4-(2-nitrobenzyl)piperazin-1-yl]methanone was selected to confirm the spatial structure through X-ray diffraction. Herbicidal activity of the target compounds was evaluated against the pre-emergence of Echinochloa crusgalli L., Lolium perenne L., Amaranthus retroflexus L. and Lactuca sativa var. ramosa Hort. Herbicidal activity of compounds with different substituent on the phenyl followed an order of magnitude that was given as: donor-drawing group > neutral group > electron-drawing group on Lactuca sativa var. ramosa Hort. (2,3-Dimethylphenyl)[4-(2-nitrobenzyl)piperazin-1-yl]methanone showed stronger herbicidal activity against the pre-emergence of Echinochloa crusgalli L. and Lolium perenne, while (2-chlorophenyl)-[4-(2-nitrobenzyl)piperazin-1-yl]methanone showed stronger herbicidal activity against Amaranthus retroflexus L. and Lactuca sativa var. ramosa Hort.
引用
收藏
页码：2567 / 2577
页数：11
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