LARGE-SCALE MANUFACTURING AND CHARACTERISATION OF EXTRACELLULAR VESICLES DERIVED FROM UMBILICAL CORD MESENCHYMAL STROMAL CELLS (MSC-EVS) IN A GMP COMPLIANT SYSTEM

被引：0
|
作者：
Rajendran, A. [1 ]
Lee, Z. [1 ]
Ganeson-Koo, M. [1 ]
Govindasamy, V. [1 ]
Then, K. [1 ,2 ]
Then, K. [1 ,2 ]
Ooi, G. [2 ]
Cheong, S. [3 ]
机构：
[1] Cryocord Malaysia Sdn Bhd, Res & Dev, Cyberjaya, Selangor, Malaysia
[2] Cryocord SDN BHD, Lab, Petaling Jaya, Selangor, Malaysia
[3] Univ Tunku Abdul Rahman, Med, Kampus Bandar Sungai Long, Kajang, Selangor, Malaysia
来源：
CYTOTHERAPY | 2023年 / 25卷 / 06期
关键词：
Cell Free therapy; Exosome; Paracrine;
D O I：
暂无
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
27
引用
收藏
页码：S20 / S21
页数：2
相关论文
共 50 条
  • [1] Procoagulant Activity of Umbilical Cord-Derived Mesenchymal Stromal Cells' Extracellular Vesicles (MSC-EVs)
    Wright, Adrienne
    Snyder, Orman
    He, Hong
    Christenson, Lane K.
    Fleming, Sherry
    Weiss, Mark L.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (11)
  • [2] GMP-compliant extracellular vesicles derived from umbilical cord mesenchymal stromal cells: manufacturing and pre-clinical evaluation in ARDS treatment
    Costa-Ferro, Zaquer Suzana Munhoz
    Rocha, Gisele Vieira
    da Silva, Katia Nunes
    Paredes, Bruno Diaz
    Loiola, Erick Correia
    Silva, Johnatas Dutra
    Santos, John Lenon de Souza
    Dias, Rosane Borges
    Figuira, Claudio Pereira
    de Oliveira, Camila Indiani
    de Moura, Ludmilla David
    Ribeiro, Ligia Nunes de Morais
    de Paula, Eneida
    Zanette, Dalila Luciola
    Rocha, Clarissa Araujo Gurgel
    Rocco, Patricia Rieken Macedo
    Souza, Bruno Solano de Freitas
    CYTOTHERAPY, 2024, 26 (09) : 1013 - 1025
  • [3] Manufacturing and characterization of extracellular vesicles from umbilical cord-derived mesenchymal stromal cells for clinical testing
    Rohde, Eva
    Pachler, Karin
    Gimona, Mario
    CYTOTHERAPY, 2019, 21 (06) : 581 - 592
  • [4] DEVELOPMENT OF MANUFACTURING THERAPEUTIC PLATFORM FOR EXTRACELLULAR VESICLES DERIVED FROM MESENCHYMAL STROMAL CELL (MSC-EVS) USING TANGENTIAL FLOW DEPTH FILTRATION (TFDF) AND TANGENTIAL FLOW FILTRATION (TFF)
    Legmann, R.
    Zakhem, E.
    Jung, J.
    Garland, C.
    Boychyn, M.
    Torres, L.
    Sinani, M.
    Breuning, C.
    Neidert, J.
    CYTOTHERAPY, 2023, 25 (06) : S189 - S189
  • [5] TOWARDS IMPROVED LARGE-SCALE MANUFACTURING PROCESSES OF MESENCHYMAL STROMAL CELL-DERIVED EXTRACELLULAR VESICLES
    Cunha, R.
    Calado, C.
    Cabral, J. M.
    da Silva, C. L.
    Fernandes-Platzgummer, A.
    CYTOTHERAPY, 2021, 23 (05) : S116 - S116
  • [6] Comprehensive miRNA Analysis of Human Umbilical Cord-Derived Mesenchymal Stromal Cells and Extracellular Vesicles
    Zou, Xiangyu
    Yu, Yongjiang
    Lin, Sihao
    Zhong, Liang
    Sun, Jie
    Zhang, Guangyuan
    Zhu, Yingjian
    KIDNEY & BLOOD PRESSURE RESEARCH, 2018, 43 (01): : 152 - 161
  • [7] Transitioning from static to suspension culture system for large-scale production of xeno-free extracellular vesicles derived from mesenchymal stromal cells
    dos Santos, Natalia Cristine Dias
    Bruzadelle-Vieira, Paula
    Noronha, Nadia de Cassia
    Mizukami-Martins, Amanda
    Orellana, Maristela Delgado
    Bentley, Maria Vitoria L. B.
    Covas, Dimas Tadeu
    Swiech, Kamilla
    Malmegrim, Kelen Cristina Ribeiro
    BIOTECHNOLOGY PROGRESS, 2024, 40 (03)
  • [8] Evaluation of Tissue Homogenization to Support the Generation of GMP-Compliant Mesenchymal Stromal Cells from the Umbilical Cord
    Emnett, Ryan J.
    Kaul, Aparna
    Babic, Aleksandar
    Geiler, Vicki
    Regan, Donna
    Gross, Gilad
    Akel, Salem
    STEM CELLS INTERNATIONAL, 2016, 2016
  • [9] Distinct Differentiation Potential of "MSC" Derived from Cord Blood and Umbilical Cord: Are Cord-Derived Cells True Mesenchymal Stromal Cells?
    Bosch, Julia
    Houben, Amelie Pia
    Radke, Teja Falk
    Stapelkamp, Daniela
    Buenemann, Erich
    Balan, Percy
    Buchheiser, Anja
    Liedtke, Stefanie
    Koegler, Gesine
    STEM CELLS AND DEVELOPMENT, 2012, 21 (11) : 1977 - 1988
  • [10] A novel approach for large-scale manufacturing of small extracellular vesicles from bone marrow-derived mesenchymal stromal cells using a hollow fiber bioreactor
    Jakl, Viktoria
    Ehmele, Melanie
    Winkelmann, Martina
    Ehrenberg, Simon
    Eiseler, Tim
    Friemert, Benedikt
    Rojewski, Markus Thomas
    Schrezenmeier, Hubert
    FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 2023, 11
12345