PET/MRI Applications in Pediatric Epilepsy

被引：4

作者：

Pedersen, Christian ^{[1
]}

Aboian, Mariam ^{[1
]}

Messina, Steven A. ^{[2
]}

Daldrup-Link, Heike ^{[3
]}

Franceschi, Ana M. ^{[4
,5
]}

机构：

[1] Yale Sch Med, Dept Radiol, New Haven, CT USA

[2] Mayo Clin Radiol, Dept Radiol, Neuroradiol Div, Rochester, MN USA

[3] Stanford Univ, Dept Radiol & Pediat, Sch Med, Palo Alto, CA USA

[4] Lenox Hill Hosp, Northwell Hlth Donald & Barbara Zucker Sch Med, Dept Radiol, Neuroradiol Div, New York, NY USA

[5] Lenox Hill Hosp, Dept Radiol, 100 East 77th St,3rd Floor, New York, NY 10075 USA

来源：

WORLD JOURNAL OF NUCLEAR MEDICINE | 2023年 / 22卷 / 02期

关键词：

hybrid imaging; PET; MRI; pediatric epilepsy; malformations of cortical development; focal cortical dysplasia; temporal lobe epilepsy; mesial temporal sclerosis; tuberous sclerosis; TUBEROUS SCLEROSIS COMPLEX; CORTICAL DYSPLASIA; PRESURGICAL EVALUATION; PROGNOSTIC PREDICTORS; EPILEPTOGENIC ZONES; TEMPORAL LOBECTOMY; SURGICAL OUTCOMES; FDG-PET; SURGERY; MRI;

D O I：

10.1055/s-0043-1764303

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Epilepsy neuroimaging assessment requires exceptional anatomic detail, physiologic and metabolic information. Magnetic resonance (MR) protocols are often time-consuming necessitating sedation and positron emission tomography (PET)/computed tomography (CT) comes with a significant radiation dose. Hybrid PET/MRI protocols allow for exquisite assessment of brain anatomy and structural abnormalities, in addition to metabolic information in a single, convenient imaging session, which limits radiation dose, sedation time, and sedation events. Brain PET/MRI has proven especially useful for accurate localization of epileptogenic zones in pediatric seizure cases, providing critical additional information and guiding surgical decision making in medically refractory cases. Accurate localization of seizure focus is necessary to limit the extent of the surgical resection, preserve healthy brain tissue, and achieve seizure control. This review provides a systematic overview with illustrative examples demonstrating the applications and diagnostic utility of PET/MRI in pediatric epilepsy.

引用

页码：78 / 86

页数：9