Progressive leukoencephalopathy as a manifestation of primary angiitis of the central nervous system: case report and review of the literature

被引：0
作者：
Stark, Adam J. [1 ]
Mobley, Bret C. [2 ]
Eaton, James E. [3 ]
机构：
[1] Vanderbilt Univ, Sch Med, Nashville, TN 37232 USA
[2] Vanderbilt Univ, Med Ctr, Dept Pathol Microbiol & Immunol, Nashville, TN 37232 USA
[3] Vanderbilt Univ, Med Ctr, Dept Neurol, 1500 21st Ave South,Suite 4333, Nashville, TN 37212 USA
来源：
JOURNAL OF NEUROLOGY | 2024年 / 271卷 / 06期
关键词：
PACNS; Leukoencephalopathy; MRI; GRANULOMATOUS-ANGIITIS;
D O I：
10.1007/s00415-024-12283-7
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Background and objective Primary angiitis of the central nervous system (PACNS) is a rare form of vasculitis solely affecting the vessels of the brain, spinal cord, and leptomeninges. A range of magnetic resonance imaging (MRI) features have been associated with PACNS, including cerebral infarction, hemorrhage, and parenchymal or leptomeningeal contrast enhancement. Methods and results We describe a 51-year-old man with a case of PACNS manifesting as akinetic mutism with progressive leukoencephalopathy. Discussion Progressive leukoencephalopathy has not been well defined as a manifestation of PACNS. We review a small number of cases with comparable features, providing additional context on this PACNS manifestation with consideration of clinical subtypes.
引用
收藏
页码：3648 / 3652
页数：5
相关论文
共 15 条
[1]  
[Anonymous], 1989, N Engl J Med, V320, P514
[2]   Recurrent leukoencephalopathy with microhemorrhages:: gradient-echo MRI study diagnostic value in CNS primary angiitis [J].
Arias, M. ;
Osorio, X. R. ;
Dapena, D. ;
Arias-Rivas, S. ;
Vazquez, F. .
MULTIPLE SCLEROSIS JOURNAL, 2008, 14 (08) :1139-1141
[3]   Primary Angiitis of the CNS A Systematic Review and Meta-analysis [J].
Beuker, Carolin ;
Strunk, Daniel ;
Rawal, Rajesh ;
Schmidt-Pogoda, Antje ;
Werring, Nils ;
Milles, Lennart ;
Ruck, Tobias ;
Wiendl, Heinz ;
Meuth, Sven ;
Minnerup, Heike ;
Minnerup, Jens .
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION, 2021, 8 (06)
[4]  
Calabrese LH, 2009, CLIN EXP RHEUMATOL, V27, pS3
[5]   PRIMARY ANGIITIS OF THE CENTRAL NERVOUS-SYSTEM - REPORT OF 8 NEW CASES, REVIEW OF THE LITERATURE, AND PROPOSAL FOR DIAGNOSTIC-CRITERIA [J].
CALABRESE, LH ;
MALLEK, JA .
MEDICINE, 1988, 67 (01) :20-39
[6]   Biopsy-proven primary angiitis of the central nervous system mimicking leukodystrophy: A case report and review of the literature [J].
Caputi, Luigi ;
Erbetta, Alessandra ;
Marucci, Gianluca ;
Pareyson, Davide ;
Eoli, Marica ;
Servida, Maura ;
Parati, Eugenio ;
Salsano, Ettore .
JOURNAL OF CLINICAL NEUROSCIENCE, 2019, 64 :42-44
[7]   Adult primary angiitis of the central nervous system: isolated small-vessel vasculitis represents distinct disease pattern [J].
de Boysson, Hubert ;
Boulouis, Gregoire ;
Aouba, Achille ;
Bienvenu, Boris ;
Guillevin, Loic ;
Zuber, Mathieu ;
Touze, Emmanuel ;
Naggara, Olivier ;
Pagnoux, Christian .
RHEUMATOLOGY, 2017, 56 (03) :439-444
[8]   SERIAL MAGNETIC-RESONANCE-IMAGING IN ISOLATED ANGIITIS OF THE CENTRAL-NERVOUS-SYSTEM [J].
EHSAN, T ;
HASAN, S ;
POWERS, JM ;
HEISERMAN, JE .
NEUROLOGY, 1995, 45 (08) :1462-1465
[9]   Idiopathic granulomatous angiitis of the CNS manifesting as diffuse white matter disease [J].
Finelli, PF ;
Onyiuke, HC ;
Uphoff, DF .
NEUROLOGY, 1997, 49 (06) :1696-1699
[10]   Radial contrast enhancement on brain magnetic resonance imaging diagnostic of primary angiitis of the central nervous system: A case report and review of the literature [J].
Ganta K. ;
Malik A.M. ;
Wood J.B. ;
Levin M.C. .
Journal of Medical Case Reports, 8 (1)
12