Diabulimia: A Risky Trend Among Adults with Type 1 Diabetes Mellitus

被引:4
作者
Ip, Eric J. [1 ,2 ]
Doroudgar, Shadi [3 ]
Salehi, Aava [2 ,3 ]
Salehi, Fojan
Najmi, Mitra [3 ,4 ]
机构
[1] Stanford Univ, Sch Med, Div Primary Care & Populat Hlth, Stanford, CA USA
[2] Kaiser Permanente Mt View Med Off, Dept Internal Med, Mountain View, CA USA
[3] Touro Univ Calif, Coll Pharm, Dept Clin Sci, Vallejo, CA 94592 USA
[4] Touro Univ Calif, Coll Pharm, 1310 Club Dr, Vallejo, CA 94592 USA
关键词
diabulimia; type; 1; diabetes; eating disorder; insulin omission; skipping insulin; weight loss; DISORDERED EATING BEHAVIOR; INSULIN RESTRICTION; ADOLESCENT FEMALES; DEPRESSION; PREVALENCE; COMPLICATIONS; ONSET; GIRLS; WOMEN;
D O I
10.1016/j.eprac.2023.08.001
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Poor adherence leads to worse glycemic control and increased complications in patients with type 1 diabetes mellitus (T1DM). Diabulimia characterizes patients with T1DM who skip or use less insulin for weight loss purposes. The study objectives were to determine: (1) the prevalence of diabulimia among adult patients with T1DM, (2) compare patients with and without diabulimia, and (3) identify factors that may place individuals at higher risk of diabulimia.Methods: A 40-item, web-based survey was administered to 21 T1DM discussion boards, Listservs, and social media outlets. The survey assessed demographics, diabetes management, psychiatric diagnoses, and screened for diabulimia. Individuals who reported intentionally skipping or using less insulin than directed for the purpose of weight loss or to prevent weight gain in the past 12 months were classified as having diabulimia.Results: Of the 225 participants who completed the survey, 8.9% had diabulimia. Patients with diabulimia had elevated hemoglobin A1C (A1C) levels (8.4% vs 6.9%; P = .014), higher rates of a diabetes-related emergency department visits or hospitalization (30.0% vs 13.2%; P = .042), and higher rates of a major depressive disorder diagnosis (40.0% vs 11.5%; P < .001) than patients without diabulimia. Factors associated with diabulimia included high A1C levels (odds ratio, 1.43; 95% CI [1.08-1.91]; P = .014) and a major depressive disorder diagnosis (odds ratio, 4.87; 95% CI [1.31-18.22]; P = .018).Conclusion: Approximately 1 in 11 adult patients with T1DM screened positive for diabulimia. Higher A1C levels and a diagnosis of major depressive disorder were associated with diabulimia.(c) 2023 AACE. Published by Elsevier Inc. All rights reserved.
引用
收藏
页码:849 / 854
页数:6
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