Pediatric T-cell Lymphoblastic Leukemia/Lymphoma Diagnosed at Routine Adenoidectomy Specimen

被引:0
作者
Kara, Iike [1 ,2 ]
Ramadan, Saime [3 ]
Senkal, Evrim [4 ]
Kocdor, Pelin [2 ,5 ]
机构
[1] Bahcesehir Univ, Fac Med, Batman Sk 66, TR-34734 Istanbul, Turkey
[2] Koc Univ, Res Ctr Translat Med, Istanbul, Turkey
[3] Baskent Univ, Dept Pathol, Istanbul, Turkey
[4] Istanbul Medeniyet Univ, Gortepe Training & Res Hosp, Dept Pediat, Istanbul, Turkey
[5] Baskent Univ, Dept Otolaryngol Head & Neck Surg, Istanbul, Turkey
关键词
adenoidectomy; tonsillectomy; pediatric; pathology; malignancy; leukemia; TONSILLECTOMY; CHILDREN;
D O I
10.1177/10668969221142044
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Postoperative routine pathologic evaluation of tonsillectomy and adenoidectomy specimens rarely reveals a diagnosis of malignancy. The object of this case report is to highlight this rare clinical occurrence. A 4-year-old boy presented with symptoms of sleep-disordered breathing and had a history of recurrent tonsillitis. Physical examination revealed adenoid hypertrophy and Brodsky Grade 1 bilateral tonsillar hypertrophy. The patient underwent adenoidectomy and tonsillectomy. The adenoids were found to be MAGS Grade 4 (Modified Adenoid Grading System) hypertrophic causing 100% obstruction. After the histologic examination, T-cell lymphoblastic leukemia/lymphoma was diagnosed. Proper treatment allowed full recovery. Currently, no consensus has been made about routine pathological evaluation. To achieve a cost-effective and precautionary approach, we recommend pathological follow-up of cases with unusual intraoperative findings with/without clinical malignancy suspicion.
引用
收藏
页码:846 / 851
页数:6
相关论文
共 21 条
  • [1] Pediatric Tonsil Cancer: A National and Institutional Perspective
    Adil, Eelam A.
    Medina, Genevieve
    Cunningham, Michael J.
    [J]. JOURNAL OF PEDIATRICS, 2018, 197 : 255 - +
  • [2] Bohr C., 2021, MED MANAG SURG PATIE, P753, DOI [10.1017/CBO9780511544590.123, DOI 10.1017/CBO9780511544590.123]
  • [3] Tonsillectomy or adenotonsillectomy versus non-surgical treatment for chronic/recurrent acute tonsillitis
    Burton, Martin J.
    Glasziou, Paul P.
    Chong, Lee Yee
    Venekamp, Roderick P.
    [J]. COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2014, (11):
  • [4] Tonsil volume, tonsil grade and obstructive sleep apnea: is there any meaningful correlation?
    Cahali, Michel Burihan
    de Paula Soares, Carolina Ferraz
    da Silva Dantas, Danielle Andrade
    Simoes Formigoni, Gilberto Guanaes
    [J]. CLINICS, 2011, 66 (08) : 1347 - 1351
  • [5] Pathologic evaluation of routine tonsillectomy and adenoidectomy specimens in the pediatric population: Is it really necessary?
    Erdag, TK
    Ecevit, MC
    Guneri, EA
    Dogan, E
    Ikiz, AO
    Sutay, S
    [J]. INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY, 2005, 69 (10) : 1321 - 1325
  • [6] Changes in incidence and indications of tonsillectomy and adenotonsillectomy, 1970-2005
    Erickson, Britt K.
    Larson, Dirk R.
    St Sauver, Jennifer L.
    Meverden, Ryan A.
    Orvidas, Laura J.
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2009, 140 (06) : 894 - 901
  • [7] The Physiopathology of T- Cell Acute Lymphoblastic Leukemia: Focus on Molecular Aspects
    Fattizzo, Bruno
    Rosa, Jessica
    Giannotta, Juri Alessandro
    Baldini, Luca
    Fracchiolla, Nicola Stefano
    [J]. FRONTIERS IN ONCOLOGY, 2020, 10
  • [8] Quality of life after tonsillectomy in children with recurrent tonsillitis
    Goldstein, Nira A.
    Stewart, Michael G.
    Witsell, David L.
    Hannley, Maureen T.
    Weaver, Edward M.
    Yueh, Bevan
    Smith, Timothy L.
    Orvidas, Laura J.
    [J]. OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2008, 138 (01) : S9 - S16
  • [9] Sleep-Disordered Breathing
    Ioachimescu, Octavian C.
    Collop, Nancy A.
    [J]. NEUROLOGIC CLINICS, 2012, 30 (04) : 1095 - +
  • [10] The New Therapeutic Strategies in Pediatric T-Cell Acute Lymphoblastic Leukemia
    Lato, Marta Weronika
    Przysucha, Anna
    Grosman, Sylwia
    Zawitkowska, Joanna
    Lejman, Monika
    [J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (09)