Synthesis and Characterization of Tween-20 Capped Biosynthesized Silver Nanoparticles for Anticancer and Antimicrobial Property

The Vitrus vinifera fruit extract was used to make silver nanoparticles (AgNPs) utilizing a green chemical technique. The biosynthesized Tween-20/Vitrus vinifera-AgNPs were observed by UV-Vis spectrophotometry. Fourier transform infrared spectroscopy, scanning transmission electron microscopy, selected area electron diffraction, and energy-dispersive X-ray spectroscopy were used to characterize the physiochemical properties. The spherical form of AgNPs was confirmed by transmission electron microscopy. The peaks in the Tween-20/Vitrus vinifera-AgNPs have an average crystallite size that is found to be 46 nm according to powder X-ray diffraction examination. Biosynthesized AgNPs had a significant effect on bone osteosarcoma MG63 cells with 55% inhibition, respectively, using MTT assay. The effective dangerous concentration of Tween-20/Vitrus vinifera with AgNP nanoparticles was less harmful to MG63 cells. The results of antibacterial activity showed that Tween-20/Vitrus vinifera-AgNPs effectively inhibited Eggerthella lenta and Staphylococcus epidermis bacteria.