OPTIMIZATION STUDY AND ANTIMICROBIAL ACTIVITY OF HEXAHYDROACRIDINE-1,8(2H,5H)-DIONE: A PROMISING COMPOUND FOR NOVEL THERAPEUTICS

被引：0

作者：

Patel, Shweta ^{[1
]}

Patel, Sarika ^{[1
]}

Parikh, Jaymin ^{[1
]}

机构：

[1] Ganpat Univ, Mehsana Urban Inst Sci, Fac Sci, Dept Chem, Mehsana 384012, Gujarat, India

来源：

HETEROCYCLIC LETTERS | 2023年 / 13卷 / 03期

关键词：

Hexahydroacridine-1; 8-dione; Morpholine; One pot multi-component reaction; Optimization study; aqueous condition; green chemistry; Antibacterial and Antifungal activity; DERIVATIVES; DICHLORIDES;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hexahydroacridine-1,8-dione is a chemical compound that has gained significant attention in medicinal chemistry and drug discovery research. This versatile building block offers a unique molecular structure that serves as a valuable precursor for the synthesis of diverse chemical scaffolds. In this research paper, we explore the synthesis and potential applications of hexahydroacridine-1,8-dione derivatives in the development of novel therapeutic agents. We develop into its pharmacological activities, including antibacterial and antifungal activity. The synthetic derivatives were confirmed using IR, 1H NMR, 13CNMR, mass spectra, and elemental analysis. The use of water as a solvent that is believed to be reasonably environmentally beneficial.

引用

页码：583 / 590

页数：8

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