Triglycerides, Obesity and Education Status Are Associated with the Risk of Developing Type 2 Diabetes in Young Adults, Cohort Study

被引:2
作者
Garbuzova, Evgeniia V. [1 ]
Shcherbakova, Lilia V. [1 ]
Rymar, Oksana D. [1 ]
Khudiakova, Alyona D. [1 ]
Shramko, Victoria S. [1 ]
Ragino, Yulia I. [1 ]
机构
[1] Russian Acad Sci IIPM Branch IC&G SB RAS, Siberian Branch, Res Inst Internal & Prevent Med, Branch Inst Cytol & Genet, Novosibirsk 630089, Russia
关键词
cohort study; persons 25-44 years old; type 2 diabetes mellitus; obesity; hypertriglyceridemia; educational status; CARDIOVASCULAR-DISEASE; GLOBAL BURDEN; MELLITUS; PREVALENCE; PROJECTIONS; POPULATION; COUNTRIES; REGISTER; THERAPY;
D O I
10.3390/jpm13091403
中图分类号
R19 [保健组织与事业(卫生事业管理)];
学科分类号
摘要
Background: It is important to determine the influence of traditional risk factors on the development of type 2 diabetes mellitus (T2DM) in young adults. Goal of the research: To study the incidence of T2DM and factors that increase the risk of its occurrence during the observation of a cohort of young adults. Materials and methods: 1341 people aged 25-44 were included in the study from 2013 to 2017, of whom 622 were men (46.4%). The examination included anamnesis, anthropometric data, and a blood test. Cases of developed T2DM were identified by comparing the Diabetes Mellitus Register, medical records of patients, and the database of examined individuals from 2019 to 2023. T2DM Results: In the examined population, 11 participants (0.82%) developed T2DM. The prevalence of T2DM was 0.96% in men and 0.69% in women. Patients with T2DM had a higher waist circumference, BMI, SBP, TG, and lower HDL than patients without T2DM, and were also less likely to have a higher education. The risk of developing T2DM increases 6.5 times at a BMI of & GE;30 kg/m2, and 5.2 times at a TG level of & GE;1.7 mmol/L, regardless of other risk factors. In the absence of a higher education, the risk of developing T2DM is increased by 5.6 times. Conclusion: In young people, high triglyceride levels, obesity, and a low level of education are associated with the risk of developing type 2 diabetes, regardless of other factors.
引用
收藏
页数:10
相关论文
共 34 条
[31]   Changes in Triglyceride Levels Over Time and Risk of Type 2 Diabetes in Young Men [J].
Tirosh, Amir ;
Shai, Iris ;
Bitzur, Rafael ;
Kochba, Ilan ;
Tekes-Manova, Dorit ;
Israeli, Eran ;
Shochat, Tzippora ;
Rudich, Assaf .
DIABETES CARE, 2008, 31 (10) :2032-2037
[32]   Global, regional, and national incidence, prevalence, and years lived with disability for 301 acute and chronic diseases and injuries in 188 countries, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013 [J].
Vos, Theo ;
Barber, Ryan M. ;
Bell, Brad ;
Bertozzi-Villa, Amelia ;
Biryukov, Stan ;
Bolliger, Ian ;
Charlson, Fiona ;
Davis, Adrian ;
Degenhardt, Louisa ;
Dicker, Daniel ;
Duan, Leilei ;
Erskine, Holly ;
Feigin, Valery L. ;
Ferrari, Alize J. ;
Fitzmaurice, Christina ;
Fleming, Thomas ;
Graetz, Nicholas ;
Guinovart, Caterina ;
Haagsma, Juanita ;
Hansen, Gillian M. ;
Hanson, Sarah Wulf ;
Heuton, Kyle R. ;
Higashi, Hideki ;
Kassebaum, Nicholas ;
Kyu, Hmwe ;
Laurie, Evan ;
Liang, Xiofeng ;
Lofgren, Katherine ;
Lozano, Rafael ;
MacIntyre, Michael F. ;
Moradi-Lakeh, Maziar ;
Naghavi, Mohsen ;
Nguyen, Grant ;
Odell, Shaun ;
Ortblad, Katrina ;
Roberts, David Allen ;
Roth, Gregory A. ;
Sandar, Logan ;
Serina, Peter T. ;
Stanaway, Jeffrey D. ;
Steiner, Caitlyn ;
Thomas, Bernadette ;
Vollset, Stein Emil ;
Whiteford, Harvey ;
Wolock, Timothy M. ;
Ye, Pengpeng ;
Zhou, Maigeng ;
Avila, Marco A. ;
Aasvang, Gunn Marit ;
Abbafati, Cristiana .
LANCET, 2015, 386 (9995) :743-800
[33]   Global prevalence of diabetes - Estimates for the year 2000 and projections for 2030 [J].
Wild, S ;
Roglic, G ;
Green, A ;
Sicree, R ;
King, H .
DIABETES CARE, 2004, 27 (05) :1047-1053
[34]   Triglyceride is an independent predictor of type 2 diabetes among middle-aged and older adults: a prospective study with 8-year follow-ups in two cohorts [J].
Zhao, Jing ;
Zhang, Yuan ;
Wei, Fengjiang ;
Song, Jiani ;
Cao, Zhi ;
Chen, Chen ;
Zhang, Kai ;
Feng, Shuzhi ;
Wang, Yaogang ;
Li, Wei-Dong .
JOURNAL OF TRANSLATIONAL MEDICINE, 2019, 17 (01)