Association Between Duration of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Positivity and Long COVID

被引:4
作者
Pozzi, Chiara [1 ,5 ]
Sarti, Riccardo [1 ,2 ]
Levi, Riccardo [1 ,2 ]
Mollura, Maximiliano [3 ]
Azzolini, Elena [1 ,2 ]
Barbieri, Riccardo [3 ]
Mantovani, Alberto [1 ,2 ,4 ]
Rescigno, Maria [1 ,2 ,5 ]
机构
[1] Humanitas Res Hosp, Ist Ricovero & Cura Carattere Sci, Milan, Italy
[2] Humanitas Univ, Dept Biomed Sci, Milan, Italy
[3] Politecn Milan, Dept Elect Informat & Bioengn, Milan, Italy
[4] Queen Mary Univ London, William Harvey Res Inst, London, England
[5] Humanitas Res Hosp, Ist Ricovero & Cura Carattere Sci, Mucosal Immunol & Microbiota Unit, Via R Levi Montalcini 4, I-20172 Pieve Emanuele, MI, Italy
关键词
long COVID; COVID-19; SARS-CoV-2; infection; vaccine;
D O I
10.1093/cid/ciad434
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
In an observational study, we analyzed 1293 healthcare workers previously infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), of which 34.1% developed postacute sequelae of SARS-CoV-2 infection (also known as long COVID). Using a multivariate logistic regression model, we demonstrate that the likelihood of developing long COVID in infected individuals rises with the increasing of duration of infection and that 3 doses of the BNT162b2 vaccine are protective, even during the Omicron wave.
引用
收藏
页码:1531 / 1533
页数:3
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