Dietary Arginine and Citrulline Supplements for Cardiovascular Health and Athletic Performance: A Narrative Review

被引:12
作者
Park, Hun-Young [1 ,2 ]
Kim, Sung-Woo [1 ,2 ]
Seo, Jisoo [2 ]
Jung, Yanghoon P. P. [3 ]
Kim, Hyunji [3 ]
Kim, Ah-Jin [3 ]
Kim, Sonwoo [3 ]
Lim, Kiwon [1 ,2 ,4 ]
机构
[1] Konkuk Univ, Phys Act & Performance Inst, Seoul 05029, South Korea
[2] Konkuk Univ, Grad Sch, Dept Sports Med & Sci, Seoul 05029, South Korea
[3] CJ CheilJedang Food & Nutr Tech, Seoul 04527, South Korea
[4] Konkuk Univ, Dept Phys Educ, Seoul 05029, South Korea
关键词
L-Arginine; L-Citrulline; citrulline malate; cardiovascular health; athletic performance; ORAL L-ARGININE; WATERMELON JUICE SUPPLEMENTATION; RESISTANCE EXERCISE PERFORMANCE; NITRIC-OXIDE SYNTHESIS; BLOOD-PRESSURE; GROWTH-HORMONE; WAVE REFLECTION; DOUBLE-BLIND; MALATE SUPPLEMENTATION; ENDOTHELIAL FUNCTION;
D O I
10.3390/nu15051268
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The global market for nutritional supplements (NS) is growing rapidly, and the use of L-arginine (Arg), L-citrulline (Cit), and citrulline malate (CitMal) supplements has been shown to enhance cardiovascular health and athletic performance. Over the past decade, Arg, Cit, and CitMal supplements have received considerable attention from researchers in the field of exercise nutrition, who have investigated their potential effects on hemodynamic function, endothelial function, aerobic and anaerobic capacity, strength, power, and endurance. Previous studies were reviewed to determine the potential impact of Arg, Cit, and CitMal supplements on cardiovascular health and exercise performance. By synthesizing the existing literature, the study aimed to provide insight into the possible uses and limitations of these supplements for these purposes. The results showed that both recreational and trained athletes did not see improved physical performance or increased nitric oxide (NO) synthesis with 0.075 g or 6 g doses of Arg supplement per body weight. However, 2.4 to 6 g of Cit per day for 7 to 16 days of various NSs had a positive impact, increasing NO synthesis, enhancing athletic performance indicators, and reducing feelings of exertion. The effects of an 8 g acute dose of CitMal supplement were inconsistent, and more research is needed to determine its impact on muscle endurance performance. Based on the positive effects reported in previous studies, further testing is warranted in various populations that may benefit from nutritional supplements, including aerobic and anaerobic athletes, resistance-trained individuals, elderly people, and clinical populations, to determine the impact of different doses, timing of ingestion, and long-term and acute effects of Arg, Cit, and CitMal supplements on cardiovascular health and athletic performance.
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页数:28
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