Electrochemical Cell-Free Biosensors for Antibody Detection

被引：33

作者：

Bracaglia, Sara ^{[1
]}

Ranallo, Simona ^{[1
]}

Ricci, Francesco ^{[1
]}

机构：

[1] Univ Roma Tor Vergata, Dept Chem, Via Ric Sci, I-00133 Rome, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2023年 / 62卷 / 08期

基金：

欧洲研究理事会;

关键词：

Antibody; DNA Nanotechnology; Electrochemical Biosensors; Synthetic Biology; CLINICALLY RELEVANT; SYNTHETIC BIOLOGY; DNA; VIRUS;

D O I：

10.1002/anie.202216512

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Programmable antigen-conjugated gene circuits which, upon recognition of a target antibody, trigger the cell-free transcription of an RNA sequence that can be consequently detected with a disposable electrochemical sensor, were designed by Sara Bracaglia, Simona Ranallo, and Francesco Ricci in their Research Article (DOI: 10.1002/anie.202216512). The cell-free electrochemical biosensor allows the sensitive, specific, selective, and multiplexed detection of different antibodies in blood serum.

引用

页数：7

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