Detection of Alzheimer's Disease Based on Cloud-Based Deep Learning Paradigm

被引:2
作者
Pruthviraja, Dayananda [1 ]
Nagaraju, Sowmyarani C. [2 ]
Mudligiriyappa, Niranjanamurthy [3 ]
Raisinghani, Mahesh S. [4 ]
Khan, Surbhi Bhatia [5 ]
Alkhaldi, Nora A. [6 ]
Malibari, Areej A. [7 ]
机构
[1] Manipal Acad Higher Educ, Manipal Inst Technol Bengaluru, Dept Informat Technol, Manipal 576104, India
[2] R V Coll Engn, Dept Comp Sci & Engn, Bengaluru 560059, India
[3] BMS Inst Technol & Management, Dept Artificial Intelligence & Machine Learning, Bengaluru 560064, India
[4] Texas Womans Univ, Coll Business, Denton, TX 76204 USA
[5] Univ Salford, Sch Sci Engn & Environm, Dept Data Sci, Manchester M54WT, England
[6] King Faisal Univ, Coll Comp Sci & Informat Technol, Dept Comp Sci, Al Hasa 31982, Saudi Arabia
[7] Princess Nourah Bint Abdulrahman Univ, Coll Engn, Dept Ind & Syst Engn, POB 84428, Riyadh 11671, Saudi Arabia
关键词
Alzheimer's disease; convolution neural network; deep learning; GoogLeNet; FEATURE REPRESENTATION; APATHY;
D O I
10.3390/diagnostics13162687
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Deep learning is playing a major role in identifying complicated structure, and it outperforms in term of training and classification tasks in comparison to traditional algorithms. In this work, a local cloud-based solution is developed for classification of Alzheimer's disease (AD) as MRI scans as input modality. The multi-classification is used for AD variety and is classified into four stages. In order to leverage the capabilities of the pre-trained GoogLeNet model, transfer learning is employed. The GoogLeNet model, which is pre-trained for image classification tasks, is fine-tuned for the specific purpose of multi-class AD classification. Through this process, a better accuracy of 98% is achieved. As a result, a local cloud web application for Alzheimer's prediction is developed using the proposed architectures of GoogLeNet. This application enables doctors to remotely check for the presence of AD in patients.
引用
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页数:15
相关论文
共 53 条
  • [1] Brain-related proteins as potential CSF biomarkers of Alzheimer's disease: A targeted mass spectrometry approach
    Begcevic, Ilijana
    Brinc, Davor
    Brown, Marshall
    Martinez-Morillo, Eduardo
    Goldhardt, Oliver
    Grimmer, Timo
    Magdolen, Viktor
    Batruch, Ihor
    Diamandis, Eleftherios P.
    [J]. JOURNAL OF PROTEOMICS, 2018, 182 : 12 - 20
  • [2] Bringas S., 2019, PROCEEDINGS, V31, P72
  • [3] Complex brain networks: graph theoretical analysis of structural and functional systems
    Bullmore, Edward T.
    Sporns, Olaf
    [J]. NATURE REVIEWS NEUROSCIENCE, 2009, 10 (03) : 186 - 198
  • [4] Biomarkers for Alzheimer's disease and other forms of dementia: Clinical needs, limitations and future aspects
    Cedazo-Minguez, Angel
    Winblad, Bengt
    [J]. EXPERIMENTAL GERONTOLOGY, 2010, 45 (01) : 5 - 14
  • [5] Cheng D, 2017, 2017 10TH INTERNATIONAL CONGRESS ON IMAGE AND SIGNAL PROCESSING, BIOMEDICAL ENGINEERING AND INFORMATICS (CISP-BMEI)
  • [6] Predicting cognitive decline with deep learning of brain metabolism and amyloid imaging
    Choi, Hongyoon
    Jin, Kyong Hwan
    [J]. BEHAVIOURAL BRAIN RESEARCH, 2018, 344 : 103 - 109
  • [7] Decreased Daytime Motor Activity Associated With Apathy in Alzheimer Disease: An Actigraphic Study
    David, Renaud
    Mulin, Emmanuel
    Friedman, Leah
    Le Duff, Franck
    Cygankiewicz, Edyta
    Deschaux, Olivier
    Garcia, Rene
    Yesavage, Jerome A.
    Robert, Philippe H.
    Zeitzer, Jamie M.
    [J]. AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY, 2012, 20 (09) : 806 - 814
  • [8] Ducksbury R., 2014, PET SPECT NEUROLOGY, P373
  • [9] Detecting Human Movement Patterns Through Data Provided by Accelerometers. A Case Study Regarding Alzheimer's Disease
    Duque, Rafael
    Nieto-Reyes, Alicia
    Martinez, Carlos
    Luis Montana, Jose
    [J]. UBIQUITOUS COMPUTING AND AMBIENT INTELLIGENCE, UCAMI 2016, PT I, 2016, 10069 : 56 - 66
  • [10] Deep learning to detect Alzheimer's disease from neuroimaging: A systematic literature review
    Ebrahimighahnavieh, Mr Amir
    Luo, Suhuai
    Chiong, Raymond
    [J]. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2020, 187