Determination of Exogenous Adrenaline Levels in Patients Undergoing Cardiopulmonary Resuscitation

被引：1
|
作者：
Altuntas, Mehmet [1 ]
Altuntas, Derya Bal [2 ]
Aslan, Sema [4 ]
Yilmaz, Ersin [3 ]
Nalbant, Ercan [1 ]
机构：
[1] Recep Tayyip Erdogan Univ, Fac Med, Dept Emergency Med, TR-53100 Rize, Turkiye
[2] Recep Tayyip Erdogan Univ, Fac Engn & Architecture, Dept Bioengn, TR-53100 Rize, Turkiye
[3] Muggla Sitki Koccman Univ, Dept Stat, TR-48170 Mugla, Turkiye
[4] Muggla Sitki Kocman Univ, Fac Sci, Dept Chem, TR-48170 Mugla, Turkiye
来源：
ACS OMEGA | 2023年 / 8卷 / 22期
关键词：
HOSPITAL CARDIAC-ARREST; CARBON-PASTE ELECTRODE; ELECTROCHEMICAL-BEHAVIOR; EPINEPHRINE; SENSOR; ACETAMINOPHEN; OUTCOMES;
D O I：
10.1021/acsomega.3c00555
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Core-shell quantum dot ZnS/CdSe screen-printedelectrodeswere used to electrochemically measure human blood plasma levels ofexogenous adrenaline administered to cardiac arrest patients. Theelectrochemical behavior of adrenaline on the modified electrode surfacewas investigated using differential pulse voltammetry (DPV), cyclicvoltammetry, and electrochemical impedance spectroscopy (EIS). Underoptimal conditions, the linear working ranges of the modified electrodewere 0.001-3 mu M (DPV) and 0.001-300 mu M (EIS).The best limit of detection for this concentration range was 2.79x 10(-8) mu M (DPV). The modified electrodesshowed good reproducibility, stability, and sensitivity and successfullydetected adrenaline levels.
引用
收藏
页码：19425 / 19432
页数：8
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