Development of Bodipy-Ir complex as an near-infrared photosensitizer for photoacoustic imaging-guided photodynamic therapy

被引：15
作者：
Liu, Chuangjun [1 ]
Jiang, Yingchun [2 ]
Xiang, Jingjing [3 ]
Xiang, Chunbai [3 ]
Li, Hongfeng [4 ]
Li, Huacheng [5 ]
Wei, Fangfang [5 ]
Huang, Jiahao [4 ]
Li, Rongqiang [1 ]
Wong, Keith Man-Chung [5 ]
Gong, Ping [3 ]
机构：
[1] Huanghuai Univ, Coll Chem & Pharmaceut Engn, Zhumadian 463000, Peoples R China
[2] Huanghuai Univ, Coll Med, Zhumadian 463000, Peoples R China
[3] Chinese Acad Sci, Shenzhen Inst Adv Technol, Shenzhen 518055, Peoples R China
[4] Southern Med Univ, Biomat Res Ctr, Sch Biomed Engn, Guangzhou 510515, Peoples R China
[5] Southern Univ Sci & Technol, Dept Chem, 1088 Xueyuan Blvd, Shenzhen 518055, Peoples R China
来源：
DYES AND PIGMENTS | 2023年 / 209卷
关键词：
NIR photosensitizer; Bodipy; Irridium; Photoacoustic imaging; Photodynamic therapy; SINGLET OXYGEN; IN-VITRO; TRIPLET SENSITIZERS; HIGHLY EFFICIENT; NANOPARTICLES; FLUORESCENCE; DERIVATIVES; GENERATION; AGENTS;
D O I：
10.1016/j.dyepig.2022.110900
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Herein we develop a novel NIR photosensitizer, bodipy-Ir. Under 808 nm excitation, bodipy-Ir could generate significant amount of singlet oxygen. In addition, bodipy-Ir exhibits photoacoustic properties as well. Thus, the photoacoustic imaging-guided photodynamic therapy of bodipy-Ir has been demonstrated.
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收藏
页数：5
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共 37 条
  • [1] Aza-BODIPY Derivatives: Enhanced Quantum Yields of Triplet Excited States and the Generation of Singlet Oxygen and their Role as Facile Sustainable Photooxygenation Catalysts
    Adarsh, Nagappanpillai
    Shanmugasundaram, Madhesh
    Avirah, Rekha R.
    Ramaiah, Danaboyina
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2012, 18 (40) : 12655 - 12662
  • [2] Tuning Photosensitized Singlet Oxygen Generation Efficiency of Novel Aza-BODIPY Dyes
    Adarsh, Nagappanpillai
    Avirah, Rekha R.
    Ramaiah, Danaboyina
    [J]. ORGANIC LETTERS, 2010, 12 (24) : 5720 - 5723
  • [3] Vascular-targeted photodynamic therapy with BF2-chelated Tetraaryl-Azadipyrromethene agents: a multi-modality molecular imaging approach to therapeutic assessment
    Byrne, A. T.
    O'Connor, A. E.
    Hall, M.
    Murtagh, J.
    O'Neill, K.
    Curran, K. M.
    Mongrain, K.
    Rousseau, J. A.
    Lecomte, R.
    McGee, S.
    Callanan, J. J.
    O'Shea, D. F.
    Gallagher, W. M.
    [J]. BRITISH JOURNAL OF CANCER, 2009, 101 (09) : 1565 - 1573
  • [4] Photodynamic therapy for cancer
    Dolmans, DEJGJ
    Fukumura, D
    Jain, RK
    [J]. NATURE REVIEWS CANCER, 2003, 3 (05) : 380 - 387
  • [5] Light Induced Antimicrobial Properties of a Brominated Boron Difluoride (BF2) Chelated Tetraarylazadipyrromethene Photosensitizer
    Frimannsson, Daniel O.
    Grossi, Marco
    Murtagh, Julie
    Paradisi, Francesca
    O'Shea, Donal F.
    [J]. JOURNAL OF MEDICINAL CHEMISTRY, 2010, 53 (20) : 7337 - 7343
  • [6] A potent nonporphyrin class of photodynamic therapeutic agent: cellular localisation, cytotoxic potential and influence of hypoxia
    Gallagher, WM
    Allen, LT
    O'Shea, C
    Kenna, T
    Hall, M
    Gorman, A
    Killoran, J
    O'Shea, DF
    [J]. BRITISH JOURNAL OF CANCER, 2005, 92 (09) : 1702 - 1710
  • [7] Carbazole-Linked Near-Infrared Aza-BODIPY Dyes as Triplet Sensitizers and Photoacoustic Contrast Agents for Deep-Tissue Imaging
    Gawale, Yogesh
    Adarsh, Nagappanpillai
    Kalva, Sandeep Kumar
    Joseph, Joshy
    Pramanik, Manojit
    Ramaiah, Danaboyina
    Sekar, Nagaiyan
    [J]. CHEMISTRY-A EUROPEAN JOURNAL, 2017, 23 (27) : 6570 - 6578
  • [8] High Affinity Neutral Bodipy Fluorophores for Mitochondrial Tracking
    Gayathri, Thumuganti
    Karnewar, Santosh
    Kotamraju, Srigiridhar
    Singh, Surya Prakash
    [J]. ACS MEDICINAL CHEMISTRY LETTERS, 2018, 9 (07): : 618 - 622
  • [9] Azadipyrromethenes: from traditional dye chemistry to leading edge applications
    Ge, Yuan
    O'Shea, Donal F.
    [J]. CHEMICAL SOCIETY REVIEWS, 2016, 45 (14) : 3846 - 3864
  • [10] Effect of AIE Substituents on the Fluorescence of Tetraphenylethene-Containing BODIPY Derivatives
    Gomez-Duran, Cesar F. Azael
    Hu, Rongrong
    Feng, Guangxue
    Li, Tingzhong
    Bu, Fan
    Arseneault, Mathieu
    Liu, Bin
    Pena-Cabrera, Eduardo
    Tang, Ben Zhong
    [J]. ACS APPLIED MATERIALS & INTERFACES, 2015, 7 (28) : 15168 - 15176
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