Nonmedication Devices in Development for the Treatment of Alzheimer's Disease

被引：0

作者：

Sleem, Tamara ^{[1
]}

Decourt, Boris ^{[2
]}

Sabbagh, Marwan N. ^{[1
]}

机构：

[1] Barrow Neurol Inst, St Josephs Hosp & Med Ctr, Dept Neurol, Phoenix, AZ USA

[2] Texas Tech Univ Hlth Sci Ctr, Sch Med, Dept Pharmacol & Neurosci, Lubbock, TX USA

来源：

JOURNAL OF ALZHEIMERS DISEASE REPORTS | 2024年 / 8卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Alzheimer's disease; clinical trials; devices; treatment; DEEP BRAIN-STIMULATION; TRANSCRANIAL MAGNETIC STIMULATION; VAGUS NERVE-STIMULATION; COGNITIVE FUNCTION; SYNAPTIC PLASTICITY; CORTEX EXCITABILITY; DOUBLE-BLIND; PHOTOBIOMODULATION; CONNECTIVITY; DEMENTIA;

D O I：

10.3233/ADR-230115

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Huge investments continue to be made in treatment for Alzheimer's disease (AD), with more than one hundred drugs currently in development. Pharmacological approaches and drug development, particularly those targeting amyloid-beta, have dominated the therapeutic landscape. At the same time, there is also a growing interest in devices for treating AD. This review aimed to identify and describe devices under development for AD treatment. In this review, we queried the devices that are in development for the treatment of AD. PubMed was searched through the end of 2021 using the terms "device," "therapeutics," and "Alzheimer's" for articles that report on devices to treat AD. Ten devices with 31 references were identified as actively being developed for the treatment of AD. Many of these devices are far along in development. Device-based therapies are often overlooked when evaluating treatment approaches to AD. However, many devices for treating AD are in development and some show promising results.

引用

页码：241 / 255

页数：15

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