Sensitivity enhancement of optical plasmon-based sensor for detection of the hemoglobin and glucose: a numerical approach

In the proposed surface plasmon resonance sensor, bimetallic plasmonic metal copper (Cu) and platinum (Pt) are coated over the BaF2 prism for the occurrence of the surface plasmon phenomena. The black phosphorous (BP) nano-sheet enhances the sensitivity for detecting water containing the solution, hemoglobin (Hb), and glucose from the body fluid samples. This paper numerically investigated the effect of the bimetal (Cu-Pt) and black phosphorous (BP) on the performance of the Kretschmann configured SPR biosensor with a visible range of 633 nm wavelength. The maximum sensitivity of 495.7 & DEG;/RIU is obtained at a sensing layer of 1.330-1.335. The angular interrogation technique optimizes the thickness of the metals and 2D material for minimum reflectance. The maximum sensitivity of 382.5 & DEG;/RIU and 399.78 & DEG;/RIU are achieved for detecting hemoglobin and glucose, respectively. The proposed work has much better sensitivity than pre-existing SPR biosensors in the Hb and glucose biosensor literature. The proposed paper can advance the research in sensing Hb and glucose in the medical field.