Loneliness during the Covid-19 pandemic in Germany: Impact of social factors and polygenic risk scores on interpersonal differences in loneliness and mental health

被引：1

作者：

von Werthern, N. M. ^{[1
,6
]}

Ahrens, K. F. ^{[1
]}

Neumann, R. J. ^{[1
]}

Kollmann, B. ^{[2
,3
]}

Kranz, T. M. ^{[1
]}

Lieb, K. ^{[2
,3
]}

Tuescher, O. ^{[2
,3
]}

Reif, A. ^{[1
]}

Fiebach, C. J. ^{[4
,5
]}

Plichta, M. M. ^{[1
]}

机构：

[1] Goethe Univ Frankfurt, Univ Hosp, Dept Psychiat Psychosomat Med & Psychotherapy, Frankfurt, Germany

[2] Univ Med Ctr Mainz, Dept Psychiat & Psychotherapy, Mainz, Germany

[3] Leibniz Inst Resilience Res LIR, Mainz, Germany

[4] Goethe Univ Frankfurt, Dept Psychol, Frankfurt, Germany

[5] Goethe Univ Frankfurt, Brain Imaging Ctr, Frankfurt, Germany

[6] Goethe Univ Frankfurt, Univ Hosp, Dept Psychiat Psychosomat Med & Psychotherapy, Heinrich Hoffmann Str 10, D-60528 Frankfurt am Main, Germany

来源：

WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY | 2023年 / 24卷 / 09期

关键词：

Loneliness; mental dysfunction; Covid-19; polygenic risk scores; lockdown; GENETIC-ANALYSIS; BEHAVIOR; PERSONALITY; ADULTS;

D O I：

10.1080/15622975.2023.2226201

中图分类号：

R749 [精神病学];

学科分类号：

100205 ;

摘要：

ObjectivesThe outbreak of Covid-19 negatively affected mental health and increased loneliness. The subjective feeling of loneliness is influenced by genetic and social factors and has a negative impact on mental health.MethodsFrom March 2020 to June 2021 loneliness was investigated in N = 517 individuals using monthly acquired questionnaire data and Latent Growth Curve Analysis. Associations of social factors and polygenic risk scores (PRSs, n = 361) with class membership were investigated.ResultsThree classes ("average", 40%; "not lonely", 38%; "elevated loneliness", 22%) were identified, that differ significantly regarding loneliness, mental dysfunction, and response to the lockdown phases. Individuals with a high PRS for neuroticism are more likely to belong to the "elevated loneliness" class, living with another person is a protective factor.ConclusionAs the "elevated loneliness" class was at the highest risk of mental dysfunction, our findings underscore the importance of identifying those individuals to implement counteractive measures.

引用

页码：838 / 848

页数：11

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